SCHEMBL145455

SCHEMBL145455

C=CCC(COCCO)OC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.39
LPAR1 Q92633 5/20 0.33
LPAR3 Q9UBY5 5/20 0.33
LPAR6 P43657 3/20 0.33
LPAR4 Q99677 3/20 0.33
LPAR5 Q9H1C0 3/20 0.33
LPAR2 Q9HBW0 3/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPK1 P28482 1/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
THRB P10828 1/20 0.31
HTT P42858 1/20 0.31
MAPT P10636 1/20 0.31
PRKD3 O94806 1/20 0.31
PRKCG P05129 1/20 0.31
PRKCB P05771 1/20 0.31
PRKCA P17252 1/20 0.31
PRKCH P24723 1/20 0.31
PRKCI P41743 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL148188 0.96 TSHR (0.41) TSHRLPAR1LPAR3LPAR6LPAR4
SCHEMBL1056917 0.83
SCHEMBL13419618 0.82 PRKD3 (0.46) TSHRLPAR1LPAR3LPAR6LPAR4
SCHEMBL25904028 0.79 LPAR1 (0.43) TSHRLPAR1LPAR3LPAR6LPAR4
SCHEMBL10310919 0.79 LPAR1 (0.43) TSHRLPAR1LPAR3LPAR6LPAR4
SCHEMBL19749216 0.77 LPAR1 (0.42) TSHRLPAR1LPAR3LPAR6LPAR4
SCHEMBL26709585 0.77 LPAR1 (0.42) TSHRLPAR1LPAR3LPAR6LPAR4
SCHEMBL12672252 0.77 TSHR (0.42) TSHRLPAR1LPAR3LPAR6LPAR4
SCHEMBL10902185 0.77 TSHR (0.33) TSHRMAPK1
SCHEMBL2108688 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107851837-B Siloxane copolymer and solid polymer electrolyte comprising the same 莫门蒂夫性能材料股份有限公司 2020-06-02 CN disclosed
US-10650938-B2 Siloxane copolymer and solid polymer electrolyte comprising such siloxane copolymers MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2020-05-12 US disclosed
EP-3329537-B1 SILOXANE COPOLYMER AND SOLID POLYMER ELECTROLYTE COMPRISING SUCH SILOXANE COPOLYMERS MOMENTIVE PERFORMANCE MAT INC (US) 2019-07-17 EP disclosed
US-20190006715-A1 SILOXANE COPOLYMER AND SOLID POLYMER ELECTROLYTE COMPRISING SUCH SILOXANE COPOLYMERS MOMENTIVE PERFORMANCE MATERIALS INC. 2019-01-03 US disclosed
EP-3329537-A1 SILOXANE COPOLYMER AND SOLID POLYMER ELECTROLYTE COMPRISING SUCH SILOXANE COPOLYMERS Momentive Performance Materials Inc. (US) 2018-06-06 EP disclosed
US-9647222-B2 Gate insulator layer for organic electronic devices MERCK PATENT GMBH (DE) 2017-05-09 US disclosed
US-9647213-B2 Interlayer for electronic devices MERCK PATENT GMBH (DE) 2017-05-09 US disclosed
US-9583713-B2 Interlayer for electronic devices MERCK PATENT GMBH (DE) 2017-02-28 US disclosed
WO-2017019475-A1 SILOXANE COPOLYMER AND SOLID POLYMER ELECTROLYTE COMPRISING SUCH SILOXANE COPOLYMERS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2017-02-02 WO disclosed
EP-2676979-B1 Gate insulator layer for electronic devices MERCK PATENT GMBH (DE) 2016-07-13 EP disclosed
EP-2676978-B1 INTERLAYER FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2015-06-24 EP disclosed
EP-2676978-A1 Interlayer for electronic devices Merck Patent GmbH (DE) 2013-12-25 EP disclosed
EP-2676979-A1 Gate insulator layer for electronic devices Merck Patent GmbH (DE) 2013-12-25 EP disclosed
CN-103413972-A Alkoxy silane electrolyte material containing oligopolyethylene glycol chain and application of electrolyte material in lithium battery propylene carbonate based electrolyte GUANGZHOU INST ENERGY CONV CAS 2013-11-27 CN disclosed
EP-2611842-A1 INTERLAYER FOR ELECTRONIC DEVICES Merck Patent GmbH (DE) 2013-07-10 EP disclosed
EP-2611841-A1 GATE INSULATOR LAYER FOR ELECTRONIC DEVICES Merck Patent GmbH (DE) 2013-07-10 EP disclosed
US-20120056249-A1 INTERLAYER FOR ELECTRONIC DEVICES PROMERUS LLC (US) 2012-03-08 US disclosed
WO-2012028278-A1 INTERLAYER FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-03-08 WO disclosed
WO-2012028279-A1 GATE INSULATOR LAYER FOR ELECTRONIC DEVICES MERCK PATENT GMBH (DE) 2012-03-08 WO disclosed
US-20120056183-A1 GATE INSULATOR LAYER FOR ORGANIC ELECTRONIC DEVICES PROMERUS LLC (US) 2012-03-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10650938-B2 Siloxane copolymer and solid polymer electrolyte comprising such siloxane copolymers HCN4, SPIN4, SPIN3 TSHR 4210/4885LPAR1 2672/4885LPAR3 2134/4885
US-20190006715-A1 SILOXANE COPOLYMER AND SOLID POLYMER ELECTROLYTE COMPRISING SUCH SILOXANE COPOLYMERS HCN4, SPIN4, SPIN3 TSHR 4210/4885LPAR1 2672/4885LPAR3 2134/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.