Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 5/20 | 0.55 |
| ▸ | GSK3B | P49841 | 5/20 | 0.51 |
| ▸ | PSD | A5PKW4 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13289337 | 0.93 | GSK3B (0.50) | CDK2GSK3BPSDCNR1MAPT | |
| SCHEMBL13289698 | 0.90 | CDK2 (0.56) | CDK2GSK3BPSDKMT2AMEN1 | |
| SCHEMBL13121694 | 0.90 | CDK2 (0.70) | CDK2GSK3B | |
| SCHEMBL14545879 | 0.88 | CDK2 (0.54) | CDK2GSK3BPSDNPC1RAB9A | |
| SCHEMBL14607199 | 0.87 | CDK2 (0.51) | CDK2GSK3BNPC1RAB9AKMT2A | |
| SCHEMBL13121616 | 0.86 | CDK2 (0.68) | CDK2GSK3BPSD | |
| SCHEMBL13121670 | 0.86 | CDK2 (0.65) | CDK2GSK3B | |
| SCHEMBL13121710 | 0.84 | CDK2 (0.63) | CDK2GSK3B | |
| SCHEMBL14301776 | 0.84 | CDK2 (0.51) | CDK2GSK3BCNR1EPHB4 | |
| SCHEMBL13121696 | 0.83 | CDK2 (0.69) | CDK2GSK3BNPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044449-A2 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2007-04-19 | — | — | WO | disclosed |