Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 3/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 4/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14413483 | 0.81 | CHEK1 (0.33) | CDK2CHEK1CCNA2CCNA1GSK3B | |
| SCHEMBL14050790 | 0.77 | GPR119 (0.34) | CDK2CCNA2 | |
| SCHEMBL14545930 | 0.70 | CHEK1 (0.34) | CDK2CHEK1CCNA2CCNA1GSK3B | |
| SCHEMBL12953240 | 0.70 | GSK3B (0.55) | CDK2CHEK1CCNA2CCNA1GSK3B | |
| SCHEMBL12953608 | 0.68 | GSK3B (0.45) | CDK2CHEK1CCNA2CCNA1GSK3B | |
| SCHEMBL12953337 | 0.68 | CDK2 (0.37) | CDK2CHEK1CCNA2CCNA1GSK3B | |
| SCHEMBL14413496 | 0.67 | CHEK1 (0.34) | CDK2CHEK1CCNA2CCNA1 | |
| SCHEMBL14545812 | 0.66 | DPP4 (0.32) | CDK2CHEK1CCNA2CCNA1 | |
| SCHEMBL12953405 | 0.66 | CDK2 (0.40) | CDK2CHEK1CCNA2CCNA1GSK3B | |
| SCHEMBL13146264 | 0.64 | CDK2 (0.37) | CDK2CHEK1CCNA2CCNA1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044449-A2 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2007-04-19 | — | — | WO | disclosed |