Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 5/20 | 0.47 |
| ▸ | CDK2 | P24941 | 10/20 | 0.45 |
| ▸ | GPR39 | O43194 | 1/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
| ▸ | GNRHR | P30968 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14607255 | 0.87 | GSK3B (0.37) | GSK3BCDK2GPR39CCNA2CCNA1 | |
| SCHEMBL14581371 | 0.86 | GSK3B (0.46) | GSK3BCDK2CCNA2CCNA1KMT2A | |
| SCHEMBL12954034 | 0.81 | GSK3B (0.45) | GSK3BCDK2GPR39CCNA2CCNA1 | |
| SCHEMBL14043231 | 0.81 | GSK3B (0.50) | GSK3BCDK2GPR39CCNA2CCNA1 | |
| SCHEMBL14418864 | 0.81 | CYP19A1 (0.41) | GSK3BCDK2CCNA2CCNA1KMT2A | |
| SCHEMBL13120694 | 0.81 | CDK2 (0.67) | GSK3BCDK2CCNA2CCNA1CCNE1 | |
| SCHEMBL14418865 | 0.80 | GSK3B (0.41) | GSK3BCDK2CCNA2CCNA1KMT2A | |
| SCHEMBL13304918 | 0.80 | GSK3B (0.62) | GSK3BCDK2GPR39CCNA2CCNA1 | |
| SCHEMBL14546006 | 0.80 | CDK2 (0.54) | GSK3BCDK2GPR39CCNA2CCNA1 | |
| SCHEMBL14613381 | 0.78 | GSK3B (0.35) | GSK3BCDK2CCNA2CCNA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044449-A2 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2007-04-19 | — | — | WO | disclosed |