SCHEMBL14546292

SCHEMBL14546292

C=CCN(C(=O)c1c(F)cccc1F)C(=O)N(C)c1ccc([S@@+]([O-])C(F)(F)F)cc1F

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RORC P51449 6/20 0.34
RORA P35398 1/20 0.32
RORB Q92753 1/20 0.32
TDP1 Q9NUW8 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4162632 1.00 RORC (0.34) RORCRORARORBTDP1
SCHEMBL4636385 0.91
SCHEMBL4153993 0.85 RORC (0.37) RORCRORARORBTDP1
SCHEMBL4145562 0.80 RORC (0.33) RORCRORARORBTDP1
SCHEMBL4636198 0.76 CES2 (0.34) RORC
SCHEMBL4148243 0.76 RORC (0.35) RORC
SCHEMBL4150845 0.76 RORC (0.35) RORCRORARORBTDP1
SCHEMBL4636452 0.71 CES2 (0.31)
SCHEMBL5314123 0.70
SCHEMBL4149643 0.69 RORC (0.31) RORCTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007046513-A2 BENZOYLUREA COMPOUNDS AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2007-04-26 WO disclosed