Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | NPC1 | O15118 | 3/20 | 0.33 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL145415 | 0.88 | TSHR (0.38) | ALDH1A1MAPK1TP53TSHRHIF1A | |
| Hydrochloric Acid SCHEMBL9015906 | 0.87 | TSHR (0.37) | ALDH1A1MAPK1TP53TSHRHIF1A | |
| SCHEMBL145683 | 0.83 | ALDH1A1 (0.48) | ALDH1A1MAPK1TP53TSHRHIF1A | |
| SCHEMBL147073 | 0.82 | ALDH1A1 (0.48) | ALDH1A1MAPK1TP53TSHRHIF1A | |
| SCHEMBL27257211 | 0.81 | ALDH1A1 (0.40) | ALDH1A1TSHRKMT2AMAPTMEN1 | |
| SCHEMBL9015899 | 0.81 | ALDH1A1 (0.40) | ALDH1A1TSHRKMT2AMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL6254389 | 0.80 | ALDH1A1 (0.47) | ALDH1A1MAPK1TP53TSHRHIF1A | |
| SCHEMBL10485681 | 0.78 | USP8 (0.37) | ALDH1A1MAPK1TP53TSHRKMT2A | |
| SCHEMBL144082 | 0.77 | ALDH1A1 (0.37) | ALDH1A1MAPK1TP53TSHRHIF1A | |
| SCHEMBL15037449 | 0.76 | ALDH1A1 (0.44) | ALDH1A1MAPK1TP53TSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11851685-B2 | Zwitterion buffer containing compositions and uses in electroanalytical devices and methods | ROCHE DIABETES CARE, INC. (US) | 2023-12-26 | — | — | US | claimed |
| US-5286362-A | Reducible substance is enzymatically reduced and oxidized at the electrode; substance formed by oxidation is different from the reducible substance used initially | BOEHRINGER MANNHEIM GMBH (DE) | 1994-02-15 | — | — | US | claimed |
| EP-4481375-A2 | DETECTION REAGENTS AND ELECTRODE ARRANGEMENTS FOR MULTI-ANALYTE DIAGNOSTIC TEST ELEMENTS, AS WELL AS METHODS OF USING THE SAME | F. Hoffmann-La Roche AG (CH) | 2024-12-25 | — | — | EP | disclosed |
| EP-3523639-B1 | DETECTION REAGENTS AND ELECTRODE ARRANGEMENTS FOR MULTI-ANALYTE DIAGNOSTIC TEST ELEMENTS, AS WELL AS METHODS OF USING THE SAME | HOFFMANN LA ROCHE (CH) | 2024-12-18 | — | — | EP | disclosed |
| US-20240327892-A1 | DETECTION REAGENTS AND ELECTRODE ARRANGEMENTS FOR MULTI-ANALYTE DIAGNOSTIC TEST ELEMENTS, AS WELL AS METHODS OF USING THE SAME | ROCHE DIABETES CARE, INC. | 2024-10-03 | — | — | US | disclosed |
| US-12024735-B2 | Detection reagents and electrode arrangements for multi-analyte diagnostic test elements, as well as methods of using the same | ROCHE DIABETES CARE, INC. (US) | 2024-07-02 | — | — | US | disclosed |
| US-11851685-B2 | Zwitterion buffer containing compositions and uses in electroanalytical devices and methods | ROCHE DIABETES CARE, INC. (US) | 2023-12-26 | — | — | US | disclosed |
| EP-4152003-A1 | SYSTEMS AND METHODS FOR MULTIPLE ANALYTE ANALYSIS | Roche Diabetes Care GmbH (DE) | 2023-03-22 | — | — | EP | disclosed |
| EP-3757574-B1 | SYSTEMS AND METHODS FOR MULTIPLE ANALYTE ANALYSIS | ROCHE DIABETES CARE GMBH (DE) | 2022-12-07 | — | — | EP | disclosed |
| US-20220275348-A1 | ZWITTERION BUFFER CONTAINING COMPOSITIONS AND USES IN ELECTROANALYTICAL DEVICES AND METHODS | ROCHE DIABETES CARE, INC. | 2022-09-01 | — | — | US | disclosed |
| US-20220098636-A1 | DETECTION REAGENTS AND ELECTRODE ARRANGEMENTS FOR MULTI-ANALYTE DIAGNOSTIC TEST ELEMENTS, AS WELL AS METHODS OF USING THE SAME | ROCHE DIABETES CARE, INC. (US) | 2022-03-31 | — | — | US | disclosed |
| US-20050013731-A1 | Test strip with slot vent opening | ROCHE DIABETES CARE, INC. | 2005-01-20 | — | — | US | disclosed |
| WO-2004113902-A1 | REAGENT STRIPE FOR TEST STRIP | ROCHE DIAGNOSTICS GMBH (DE) | 2004-12-29 | — | — | WO | disclosed |
| WO-2004113901-A1 | TEST STRIP WITH SLOT VENT OPENING | ROCHE DIAGNOSTICS GMBH (DE) | 2004-12-29 | — | — | WO | disclosed |
| WO-2004113900-A2 | TEST STRIP WITH FLARED SAMPLE RECEIVING CHAMBER | ROCHE DIAGNOSTICS GMBH (DE) | 2004-12-29 | — | — | WO | disclosed |
| EP-0441222-B1 | Process and electrode system for determining an analyte or an oxidoreductase as well as suitable compounds | BOEHRINGER MANNHEIM GMBH (DE) | 1996-12-18 | — | — | EP | disclosed |
| US-5286362-A | Reducible substance is enzymatically reduced and oxidized at the electrode; substance formed by oxidation is different from the reducible substance used initially | BOEHRINGER MANNHEIM GMBH (DE) | 1994-02-15 | — | — | US | disclosed |
| US-5122244-A | Having a reducible nitroso or oxime compound to transfer electrons leading to a signal and form an aromatic amine oxidizable to a compound different from the original; low voltage | BOEHRINGER MANNHEIM GMBH (DE) | 1992-06-16 | — | — | US | disclosed |
| CN-1054666-A | Be used for the method for electrochemical determination of analyte or oxidoreducing enzyme and sensitive electrode system and for this reason and the compound that uses | BOEHRINGER MANNHEIM GMBH (DE) | 1991-09-18 | — | — | CN | disclosed |
| EP-0441222-A2 | Process and electrode system for determining an analyte or an oxidoreductase as well as suitable compounds | Roche Diagnostics GmbH (DE) | 1991-08-14 | — | — | EP | disclosed |