Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6254389 | 0.98 | ALDH1A1 (0.47) | ALDH1A1TSHRHSD17B10MAPK1TP53 | |
| SCHEMBL10025577 | 0.89 | KMT2A (0.51) | ALDH1A1TSHRHSD17B10MAPK1TP53 | |
| SCHEMBL8007581 | 0.88 | ALDH1A1 (0.45) | ALDH1A1TSHRHSD17B10MAPK1TP53 | |
| SCHEMBL11914176 | 0.88 | ALDH1A1 (0.43) | ALDH1A1TSHRHSD17B10MAPK1TP53 | |
| Hydrochloric Acid SCHEMBL17847422 | 0.87 | KMT2A (0.50) | ALDH1A1TSHRHSD17B10MAPK1TP53 | |
| SCHEMBL145415 | 0.87 | TSHR (0.38) | ALDH1A1TSHRHSD17B10MAPK1TP53 | |
| SCHEMBL9437766 | 0.86 | ALDH1A1 (0.40) | ALDH1A1TSHRHSD17B10MAPK1TP53 | |
| Hydrochloric Acid SCHEMBL9015906 | 0.85 | TSHR (0.37) | ALDH1A1TSHRHSD17B10MAPK1TP53 | |
| SCHEMBL13452275 | 0.84 | KMT2A (0.58) | ALDH1A1TSHRHSD17B10MAPK1TP53 | |
| Hydrochloric Acid SCHEMBL5816747 | 0.84 | ALDH1A1 (0.40) | ALDH1A1TSHRHSD17B10MAPK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11851685-B2 | Zwitterion buffer containing compositions and uses in electroanalytical devices and methods | ROCHE DIABETES CARE, INC. (US) | 2023-12-26 | — | — | US | claimed |
| US-9926536-B2 | Glucose oxidase variants and methods of using the same | ROCHE DIABETES CARE, INC. (US) | 2018-03-27 | — | — | US | claimed |
| US-20160002609-A1 | Glucose Oxidase Variants, As Well As Compositions, Devices, Kits and Uses Thereof | ROCHE DIABETES CARE, INC. (US) | 2016-01-07 | — | — | US | claimed |
| EP-2948547-A1 | NOVEL GLUCOSE OXIDASES DERIVED FROM ASPERGILLUS NIGER | Roche Diagnostics GmbH (DE) | 2015-12-02 | — | — | EP | claimed |
| US-8962271-B2 | Fructosyl peptidyl oxidase | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2015-02-24 | — | — | US | claimed |
| EP-2462239-B1 | Fructosyl peptidyl oxidase and sensor for assaying a glycated protein | ROCHE DIAGNOSTICS GMBH (DE) | 2014-09-17 | — | — | EP | claimed |
| US-20140227728-A1 | NOVEL FRUCTOSYL PEPTIDYL OXIDASE | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2014-08-14 | — | — | US | claimed |
| WO-2014114810-A1 | NOVEL GLUCOSE OXIDASES DERIVED FROM ASPERGILLUS NIGER | ROCHE DIAGNOSTICS GMBH (DE) | 2014-07-31 | — | — | WO | claimed |
| US-8721853-B2 | Fructosyl peptidyl oxidase | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2014-05-13 | — | — | US | claimed |
| US-20120202235-A1 | NOVEL FRUCTOSYL PEPTIDYL OXIDASE | ROCHE DIAGNOSTICS OPERATIONS, INC. | 2012-08-09 | — | — | US | claimed |
| US-5286362-A | Reducible substance is enzymatically reduced and oxidized at the electrode; substance formed by oxidation is different from the reducible substance used initially | BOEHRINGER MANNHEIM GMBH (DE) | 1994-02-15 | — | — | US | claimed |
| EP-0403797-A2 | The use of a light stabilizer comprising an aryl nitrogen compound for stabilizing an organic dye | TAIYO YUDEN CO., LTD. (JP) | 1990-12-27 | — | — | EP | claimed |
| EP-4481375-A2 | DETECTION REAGENTS AND ELECTRODE ARRANGEMENTS FOR MULTI-ANALYTE DIAGNOSTIC TEST ELEMENTS, AS WELL AS METHODS OF USING THE SAME | F. Hoffmann-La Roche AG (CH) | 2024-12-25 | — | — | EP | disclosed |
| EP-3523639-B1 | DETECTION REAGENTS AND ELECTRODE ARRANGEMENTS FOR MULTI-ANALYTE DIAGNOSTIC TEST ELEMENTS, AS WELL AS METHODS OF USING THE SAME | HOFFMANN LA ROCHE (CH) | 2024-12-18 | — | — | EP | disclosed |
| US-12116610-B2 | Glycerol 3-phosphate oxidase mutants, compositions, devices, kits and uses thereof | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2024-10-15 | — | — | US | disclosed |
| US-20240327892-A1 | DETECTION REAGENTS AND ELECTRODE ARRANGEMENTS FOR MULTI-ANALYTE DIAGNOSTIC TEST ELEMENTS, AS WELL AS METHODS OF USING THE SAME | ROCHE DIABETES CARE, INC. | 2024-10-03 | — | — | US | disclosed |
| EP-0354441-A2 | Method for the colorimetric determination of analyte using enzymatic oxydation | Roche Diagnostics GmbH (DE) | 1990-02-14 | — | — | EP | disclosed |
| US-4702863-A | Indoaniline and indophenol compounds, a process for their preparation, dyeing compositions containing them and a hair-dyeing process | L'OREAL (FR) | 1987-10-27 | — | — | US | disclosed |
| US-4093806-A | HAIR DYES | L'OREAL (FR) | 1978-06-06 | — | — | US | disclosed |
| US-4046786-A | HAIR DYES | L'OREAL (FR) | 1977-09-06 | — | — | US | disclosed |