SCHEMBL14546641

SCHEMBL14546641

CCCCn1c2c(c3cc(C(c4ccc(N(C)c5ccccc5)cc4)c4ccc(N(C)c5ccccc5)cc4)ccc31)C=CCC2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RORA P35398 5/20 0.38
RORC P51449 5/20 0.38
RORB Q92753 5/20 0.38
NPC1 O15118 4/20 0.34
RAB9A P51151 3/20 0.34
KDM4E B2RXH2 2/20 0.34
PABPC1 P11940 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
PKM P14618 1/20 0.34
ATM Q13315 1/20 0.34
CNR2 P34972 3/20 0.32
SIRT2 Q8IXJ6 2/20 0.32
APOBEC3A P31941 1/20 0.31
APOBEC3G Q9HC16 1/20 0.31
PGR P06401 5/20 0.31
ALDH1A1 P00352 2/20 0.31
NTSR1 P30989 1/20 0.31
NLRP3 Q96P20 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29576546 0.80 RORA (0.50) RORARORCRORBNPC1CNR2
SCHEMBL398421 0.80 RORA (0.50) RORARORCRORBNPC1CNR2
SCHEMBL10225069 0.74 NPC1 (0.35) RORARORCRORBNPC1RAB9A
SCHEMBL14526612 0.70 MAPT (0.49) RORCKDM4EMEN1KMT2APKM
SCHEMBL279246 0.68 CNR2 (0.52) RORARORCRORBNPC1CNR2
SCHEMBL25827410 0.64 KDM4E (0.33) KDM4EATM
SCHEMBL26407841 0.63 KDM4E (0.47) NPC1RAB9AKDM4EMEN1KMT2A
SCHEMBL9659560 0.63 NR3C2 (0.46) NPC1RAB9AKDM4EMEN1KMT2A
SCHEMBL14781275 0.63 GRIN2D (0.38) RORARORCRORBRAB9AKDM4E
SCHEMBL3740935 0.62 RORA (0.52) RORARORCRORBNPC1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7198884-B2 Heat stable photocurable resin composition for dry film resist CIBA SPECIALTY CHEMICALS CORP. (US) 2007-04-03 US disclosed