SCHEMBL398421

SCHEMBL398421

CCCCn1c2ccccc2c2cc(C(c3ccc(N(C)c4ccccc4)cc3)c3ccc(N(C)c4ccccc4)cc3)ccc21

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
RORA P35398 5/20 0.50
RORC P51449 5/20 0.50
RORB Q92753 5/20 0.50
CNR2 P34972 10/20 0.46
PGR P06401 4/20 0.44
ALDH1A1 P00352 2/20 0.43
HPGD P15428 1/20 0.43
NPC1 O15118 1/20 0.41
CNR1 P21554 1/20 0.40
PSEN1 P49768 2/20 0.40
PSEN2 P49810 2/20 0.40
APH1B Q8WW43 2/20 0.40
NCSTN Q92542 2/20 0.40
APH1A Q96BI3 2/20 0.40
PSENEN Q9NZ42 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29576546 1.00 RORA (0.50) RORARORCRORBCNR2PGR
SCHEMBL14526612 0.88 MAPT (0.49) RORCALDH1A1HPGD
SCHEMBL279246 0.88 CNR2 (0.52) RORARORCRORBCNR2PGR
SCHEMBL3740935 0.81 RORA (0.52) RORARORCRORBCNR2PGR
SCHEMBL279641 0.80 HPGD (0.57) RORCCNR2PGRALDH1A1HPGD
SCHEMBL14546641 0.80 RORA (0.38) RORARORCRORBCNR2PGR
SCHEMBL4635172 0.78 MAPT (0.51) RORCALDH1A1HPGDNPC1
SCHEMBL18763391 0.76 RORA (0.49) RORARORCRORBCNR2PGR
SCHEMBL3156176 0.76 MAPT (0.58) RORCALDH1A1HPGD
SCHEMBL279090 0.74 MAPT (0.56) RORCALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 154 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4644130-A2 A COMPOSITION DataLase Ltd. (GB) 2025-11-05 EP claimed
US-20240182760-A1 A COMPOSITION DATALASE LTD. (GB) 2024-06-06 US claimed
EP-4305095-A1 A COMPOSITION DataLase Ltd (GB) 2024-01-17 EP claimed
US-20240010020-A1 A COMPOSITION DATALASE LTD. (GB) 2024-01-11 US claimed
US-7198884-B2 Heat stable photocurable resin composition for dry film resist CIBA SPECIALTY CHEMICALS CORP. (US) 2007-04-03 US claimed
US-20050260520-A1 Heat stable photocurable resin composition for dry film resist CIBA SPECIALTY CHEMICALS CORP. 2005-11-24 US claimed
EP-1520209-A1 HEAT STABLE PHOTOCURABLE RESIN COMPOSITION FOR DRY FILM RESIST Ciba SC Holding AG (CH) 2005-04-06 EP claimed
WO-2004008251-A1 HEAT STABLE PHOTOCURABLE RESIN COMPOSITION FOR DRY FILM RESIST CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-01-22 WO claimed
JP-5201144-A None JP disclosed
EP-4644130-A2 A COMPOSITION DataLase Ltd. (GB) 2025-11-05 EP disclosed
US-20250197597-A1 A PLASTIC PRODUCT DATALASE LTD. (GB) 2025-06-19 US disclosed
US-12285961-B2 Heat transfer agents in an image-forming composition DATALASE LTD. (GB) 2025-04-29 US disclosed
EP-4490230-A1 A PLASTIC PRODUCT DataLase Ltd. (GB) 2025-01-15 EP disclosed
US-20240182760-A1 A COMPOSITION DATALASE LTD. (GB) 2024-06-06 US disclosed
EP-0188377-A1 New phthalide derivatives KANZAKI PAPER MANUFACTURING CO., LTD (JP) 1986-07-23 EP disclosed
EP-0171795-A2 Self-contained type pressure sensitive record sheet KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1986-02-19 EP disclosed
EP-0127203-A1 New phthalide derivatives, process for preparing the same and recording system utilizing the same as colourless chromogenic material KANZAKI PAPER MANUFACTURING CO., LTD (JP) 1984-12-05 EP disclosed
US-4486762-A CHROMOGEN, COLOR ACCEPTOR, PULP POWER KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1984-12-04 US disclosed
US-4435340-A EMULSION POLYMERIZATION OF AN AROMATIC POLYISOCYANATE AND AN ALIPHATIC DIISOCYANATE TO ENCAPSULATE A CHROMAGEN; STORAGE STABILITY KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1984-03-06 US disclosed
EP-0062544-A1 New phthalide derivatives, process for preparing the same and recording system utilizing the same as colourless chromogenic material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1982-10-13 EP disclosed