Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | PHLPP2 | Q6ZVD8 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | SENP2 | Q9HC62 | 3/20 | 0.38 |
| ▸ | SENP3 | Q9H4L4 | 2/20 | 0.38 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.38 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.38 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.38 |
| ▸ | ATIC | P31939 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14546954 | 0.94 | PHLPP2 (0.44) | THRBPHLPP2HSD17B10CYP2C9CYP2C19 | |
| SCHEMBL14546920 | 0.93 | THRB (0.41) | THRBPHLPP2HSD17B10CYP2C9CYP2C19 | |
| SCHEMBL14546741 | 0.89 | THRB (0.45) | THRBPHLPP2HSD17B10CYP2C9CYP2C19 | |
| SCHEMBL14546774 | 0.86 | THRB (0.48) | THRBPHLPP2HSD17B10CYP2C9CYP2C19 | |
| SCHEMBL14546984 | 0.86 | THRB (0.43) | THRBPHLPP2HSD17B10CYP2C9CYP2C19 | |
| SCHEMBL14547024 | 0.86 | THRB (0.46) | THRBHSD17B10CYP2C9CYP2C19SENP2 | |
| SCHEMBL14546748 | 0.83 | TP53 (0.40) | THRBPHLPP2HSD17B10CYP2C9CYP2C19 | |
| SCHEMBL13793159 | 0.83 | THRB (0.45) | THRBPHLPP2HSD17B10CYP2C9CYP2C19 | |
| SCHEMBL12052897 | 0.83 | THRB (0.45) | THRBPHLPP2HSD17B10CYP2C9CYP2C19 | |
| SCHEMBL14547026 | 0.83 | THRB (0.43) | THRBPHLPP2HSD17B10CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039573-A2 | AZO REACTIVE DYES AND MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND THEIR USE | DYSTAR TEXTILFARBEN GMBH & CO DEUTSCHLAND KG (DE) | 2007-04-12 | — | — | WO | disclosed |