Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | PHLPP2 | Q6ZVD8 | 4/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ATIC | P31939 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 4/20 | 0.37 |
| ▸ | BRD3 | Q15059 | 2/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.37 |
| ▸ | BRD2 | P25440 | 1/20 | 0.37 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SENP2 | Q9HC62 | 3/20 | 0.37 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.37 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.37 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | SENP3 | Q9H4L4 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14546748 | 0.95 | TP53 (0.40) | THRBPHLPP2ENPP2CYP2C9CYP2C19 | |
| SCHEMBL14547026 | 0.94 | THRB (0.43) | THRBPHLPP2ENPP2CYP2C9CYP2C19 | |
| SCHEMBL14546913 | 0.93 | THRB (0.42) | THRBPHLPP2ENPP2CYP2C9CYP2C19 | |
| SCHEMBL12052869 | 0.91 | THRB (0.39) | THRBPHLPP2ENPP2CYP2C9CYP2C19 | |
| SCHEMBL14546910 | 0.90 | BRD4 (0.37) | THRBPHLPP2ENPP2CYP2C9CYP2C19 | |
| SCHEMBL14546994 | 0.90 | BRD4 (0.37) | THRBPHLPP2ENPP2CYP2C9CYP2C19 | |
| SCHEMBL14546909 | 0.89 | THRB (0.44) | THRBPHLPP2ENPP2CYP2C9CYP2C19 | |
| SCHEMBL14546970 | 0.88 | PHLPP2 (0.37) | THRBPHLPP2ENPP2CYP2C9CYP2C19 | |
| SCHEMBL14546742 | 0.88 | ENPP2 (0.42) | THRBPHLPP2ENPP2CYP2C9CYP2C19 | |
| SCHEMBL14546744 | 0.87 | P2RX5 (0.38) | THRBENPP2CYP2C19ATICRPS6KA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039573-A2 | AZO REACTIVE DYES AND MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND THEIR USE | DYSTAR TEXTILFARBEN GMBH & CO DEUTSCHLAND KG (DE) | 2007-04-12 | — | — | WO | disclosed |