Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.41 |
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.40 |
| ▸ | SENP2 | Q9HC62 | 4/20 | 0.36 |
| ▸ | SLC7A11 | Q9UPY5 | 3/20 | 0.36 |
| ▸ | SUMO2 | P61956 | 3/20 | 0.36 |
| ▸ | SUMO1 | P63165 | 3/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.36 |
| ▸ | CD40 | P25942 | 1/20 | 0.35 |
| ▸ | CD40LG | P29965 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14546966 | 1.00 | THRB (0.43) | THRBENPP2PHLPP2SENP2SLC7A11 | |
| SCHEMBL14546985 | 1.00 | THRB (0.43) | THRBENPP2PHLPP2SENP2SLC7A11 | |
| SCHEMBL14546918 | 0.95 | THRB (0.36) | THRBENPP2PHLPP2SENP2SUMO2 | |
| SCHEMBL12053049 | 0.91 | THRB (0.38) | THRBENPP2PHLPP2SENP2SLC7A11 | |
| SCHEMBL12053044 | 0.91 | THRB (0.38) | THRBENPP2PHLPP2SENP2SLC7A11 | |
| SCHEMBL12053051 | 0.91 | THRB (0.38) | THRBENPP2PHLPP2SENP2SLC7A11 | |
| SCHEMBL14546752 | 0.91 | THRB (0.48) | THRBENPP2PHLPP2SENP2SLC7A11 | |
| SCHEMBL14546784 | 0.91 | THRB (0.48) | THRBENPP2PHLPP2SENP2SLC7A11 | |
| SCHEMBL14546919 | 0.90 | THRB (0.43) | THRBENPP2PHLPP2SENP2SLC7A11 | |
| SCHEMBL14546963 | 0.90 | THRB (0.43) | THRBENPP2PHLPP2SENP2SLC7A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039573-A2 | AZO REACTIVE DYES AND MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND THEIR USE | DYSTAR TEXTILFARBEN GMBH & CO DEUTSCHLAND KG (DE) | 2007-04-12 | — | — | WO | disclosed |