Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.36 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.35 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.31 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.31 |
| ▸ | SENP2 | Q9HC62 | 2/20 | 0.31 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.31 |
| ▸ | CD40 | P25942 | 1/20 | 0.31 |
| ▸ | CD40LG | P29965 | 1/20 | 0.31 |
| ▸ | SLC7A11 | Q9UPY5 | 3/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12053051 | 1.00 | THRB (0.38) | THRBENPP2PHLPP2SUMO2SUMO1 | |
| SCHEMBL12053049 | 1.00 | THRB (0.38) | THRBENPP2PHLPP2SUMO2SUMO1 | |
| SCHEMBL12053025 | 0.96 | THRB (0.32) | THRBENPP2PHLPP2 | |
| SCHEMBL12053087 | 0.93 | ENPP2 (0.43) | THRBENPP2PHLPP2CD40CD40LG | |
| SCHEMBL12052811 | 0.92 | THRB (0.42) | THRBENPP2PHLPP2SUMO2SUMO1 | |
| SCHEMBL12052516 | 0.92 | THRB (0.42) | THRBENPP2PHLPP2SUMO2SUMO1 | |
| SCHEMBL14546985 | 0.91 | THRB (0.43) | THRBENPP2PHLPP2SUMO2SUMO1 | |
| SCHEMBL14546966 | 0.91 | THRB (0.43) | THRBENPP2PHLPP2SUMO2SUMO1 | |
| SCHEMBL14546965 | 0.91 | THRB (0.43) | THRBENPP2PHLPP2SUMO2SUMO1 | |
| SCHEMBL12053076 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8080101-B2 | Azo reactive dyes and mixtures of fiber-reactive azo dyes, their preparation and their use | DYSTAR COLOURS DEUTSCHLAND GMBH (DE) | 2011-12-20 | — | — | US | disclosed |
| US-20080295732-A1 | Azo Reactive Dyes And Mixtures Of Fiber-Reactive Azo Dyes, Their Preparation And Their Use | DYSTAR TEXTILFARBEN GMBH &CO. DEUTSCHLAND KG (DE) | 2008-12-04 | — | — | US | disclosed |