Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 3/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 3/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 3/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.34 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.34 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12195777 | 0.85 | HDAC1 (0.51) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL13465162 | 0.81 | HDAC1 (0.70) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL1521164 | 0.81 | HDAC1 (0.70) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL1521160 | 0.81 | HDAC1 (0.70) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL1521161 | 0.69 | HDAC1 (0.69) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL1521166 | 0.69 | HDAC1 (0.69) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL28381722 | 0.69 | CA12 (0.40) | HDAC1HDAC3HDAC2CSNK2A2CSNK2B | |
| SCHEMBL12963995 | 0.69 | RECQL (0.48) | HDAC1HDAC3HDAC2CSNK2A2CSNK2B | |
| SCHEMBL8089729 | 0.69 | HDAC3 (0.40) | HDAC1HDAC3HDAC4HDAC7HDAC2 | |
| SCHEMBL12245834 | 0.69 | HDAC1 (0.68) | HDAC1HDAC3HDAC4HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070093413-A1 | Histone deacetylases, and uses related thereto | HARVARD UNIVERSITY OTI (US) | 2007-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070093413-A1 | Histone deacetylases, and uses related thereto | HDAC1, HDAC8, HDAC11 | HDAC1 1/4885HDAC3 20/4885HDAC4 9/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.