Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.38 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.38 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.38 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12963995 | 0.83 | RECQL (0.48) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL19520246 | 0.77 | ALDH1A1 (0.52) | ALDH1A1HPGDKMT2AHDAC1MAPK1 | |
| SCHEMBL912761 | 0.76 | KMT2A (0.56) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL25214258 | 0.75 | CES2 (0.50) | CA1CA2ALDH1A1HPGDRAB9A | |
| SCHEMBL27509219 | 0.75 | KMT2A (0.36) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL20944778 | 0.74 | KMT2A (0.55) | ALDH1A1HSD17B10RECQLCYP3A4KMT2A | |
| SCHEMBL3274886 | 0.74 | KMT2A (0.55) | ALDH1A1HSD17B10RECQLCYP3A4KMT2A | |
| Hydrochloric Acid SCHEMBL8526625 | 0.74 | KMT2A (0.54) | CA12CA1CA2CA9ALDH1A1 | |
| SCHEMBL2905480 | 0.74 | ALDH1A1 (0.60) | CA12CA1CA2ALDH1A1HSD17B10 | |
| SCHEMBL4140392 | 0.73 | CES2 (0.52) | CA12CA1CA2ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | claimed |