Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14546998 | 0.91 | ENPP1 (0.37) | MAPTKDM4ETDP1MEN1KMT2A | |
| SCHEMBL14546906 | 0.90 | KDM4E (0.40) | MAPTKDM4ETDP1MEN1KMT2A | |
| SCHEMBL14546780 | 0.89 | PRMT1 (0.42) | MAPTKDM4ETDP1MEN1KMT2A | |
| SCHEMBL14547032 | 0.87 | TDP1 (0.45) | MAPTKDM4ETDP1MEN1KMT2A | |
| SCHEMBL14546750 | 0.87 | KDM4E (0.42) | MAPTKDM4ETDP1MEN1KMT2A | |
| SCHEMBL14546986 | 0.87 | PRMT1 (0.43) | MAPTKDM4ETDP1MEN1KMT2A | |
| SCHEMBL12053247 | 0.87 | MAPT (0.39) | MAPTKDM4ETDP1MEN1KMT2A | |
| SCHEMBL14546980 | 0.86 | ENPP1 (0.35) | MAPTKDM4ETDP1MEN1KMT2A | |
| SCHEMBL14546914 | 0.86 | THRB (0.44) | MAPTKDM4ETDP1MEN1KMT2A | |
| SCHEMBL14547034 | 0.85 | PRMT1 (0.46) | MAPTKDM4ETDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039573-A2 | AZO REACTIVE DYES AND MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND THEIR USE | DYSTAR TEXTILFARBEN GMBH & CO DEUTSCHLAND KG (DE) | 2007-04-12 | — | — | WO | disclosed |