Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.37 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | P2RX5 | Q93086 | 2/20 | 0.35 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.35 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14546750 | 0.93 | KDM4E (0.42) | TDP1KDM4EMAPTRAB9AMEN1 | |
| SCHEMBL14546744 | 0.90 | P2RX5 (0.38) | TDP1KDM4EMAPTRAB9AMEN1 | |
| SCHEMBL14547034 | 0.90 | PRMT1 (0.46) | TDP1KDM4EMAPTRAB9AMEN1 | |
| SCHEMBL14546906 | 0.89 | KDM4E (0.40) | TDP1KDM4EMAPTRAB9AMEN1 | |
| SCHEMBL14546780 | 0.87 | PRMT1 (0.42) | TDP1KDM4EMAPTRAB9AMEN1 | |
| SCHEMBL14547008 | 0.87 | MAPT (0.43) | TDP1KDM4EMAPTRAB9AMEN1 | |
| SCHEMBL12053223 | 0.86 | KDM4E (0.41) | TDP1KDM4EMAPTRAB9AMEN1 | |
| SCHEMBL14546986 | 0.85 | PRMT1 (0.43) | TDP1KDM4EMAPTRAB9AMEN1 | |
| SCHEMBL14546921 | 0.85 | NSD2 (0.37) | TDP1KDM4EMAPTRAB9AMEN1 | |
| SCHEMBL14546913 | 0.85 | THRB (0.42) | TDP1KDM4EMAPTRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007039573-A2 | AZO REACTIVE DYES AND MIXTURES OF FIBER-REACTIVE AZO DYES, THEIR PREPARATION AND THEIR USE | DYSTAR TEXTILFARBEN GMBH & CO DEUTSCHLAND KG (DE) | 2007-04-12 | — | — | WO | disclosed |