Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 15/20 | 0.45 |
| ▸ | CDK2 | P24941 | 6/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13998513 | 0.78 | GSK3B (0.59) | GSK3BCDK2CCNE1 | |
| SCHEMBL13998518 | 0.77 | MAPT (0.55) | GSK3BCDK2CCNE1 | |
| SCHEMBL13998482 | 0.76 | GSK3B (0.68) | GSK3BCDK2CCNE1 | |
| SCHEMBL13998528 | 0.75 | GSK3B (0.62) | GSK3BCDK2CCNE1 | |
| SCHEMBL13998521 | 0.74 | GSK3B (0.70) | GSK3BCDK2CCNE1 | |
| SCHEMBL13998503 | 0.73 | GSK3B (0.70) | GSK3BCDK2CCNE1 | |
| SCHEMBL13998494 | 0.73 | GSK3B (0.71) | GSK3BCDK2CCNE1 | |
| SCHEMBL13998461 | 0.73 | GSK3B (0.82) | GSK3BCDK2CCNE1 | |
| SCHEMBL13998583 | 0.72 | GSK3B (0.49) | GSK3BCDK2CCNE1 | |
| SCHEMBL14547158 | 0.72 | GSK3B (0.49) | GSK3BCDK2CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044401-A2 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2007-04-19 | — | — | WO | disclosed |