Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 5/20 | 0.48 |
| ▸ | CHEK1 | O14757 | 13/20 | 0.44 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.44 |
| ▸ | CDK2 | P24941 | 5/20 | 0.44 |
| ▸ | CCNA1 | P78396 | 5/20 | 0.44 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14547312 | 0.79 | TRPC3 (0.43) | GSK3B | |
| SCHEMBL14547159 | 0.79 | GSK3B (0.40) | GSK3B | |
| SCHEMBL14547251 | 0.79 | CDK2 (0.33) | GSK3BCHEK1CCNA2CDK2CCNA1 | |
| SCHEMBL14547249 | 0.79 | CDK2 (0.33) | GSK3BCHEK1CCNA2CDK2CCNA1 | |
| SCHEMBL14043181 | 0.77 | GSK3B (0.60) | GSK3BCHEK1CCNA2CDK2CCNA1 | |
| SCHEMBL14547314 | 0.75 | GSK3B (0.52) | GSK3BCHEK1CCNA2CDK2CCNA1 | |
| SCHEMBL14547313 | 0.75 | CDK2 (0.37) | GSK3BCHEK1CCNA2CDK2CCNA1 | |
| SCHEMBL12953557 | 0.73 | CHEK1 (0.73) | GSK3BCHEK1CCNA2CDK2CCNA1 | |
| SCHEMBL12953331 | 0.72 | GSK3B (0.55) | GSK3BCHEK1CCNA2CDK2CCNA1 | |
| SCHEMBL12953644 | 0.72 | GSK3B (0.62) | GSK3BCHEK1CCNA2CDK2CCNA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007044401-A2 | NOVEL PYRAZOLOPYRIMIDINES AS CYCLIN DEPENDENT KINASE INHIBITORS | SCHERING CORPORATION (US) | 2007-04-19 | — | — | WO | disclosed |