Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.53 |
| ▸ | TNFSF11 | O14788 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
| ▸ | FABP4 | P15090 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1630738 | 0.85 | HTR6 (0.47) | HTR6TNFSF11KMT2AALDH1A1HTT | |
| SCHEMBL5204149 | 0.82 | ALDH1A1 (0.45) | HTR6KMT2AALDH1A1L3MBTL1HTT | |
| SCHEMBL23611854 | 0.79 | HTR6 (0.46) | HTR6KMT2AALDH1A1L3MBTL1HTT | |
| SCHEMBL22777950 | 0.78 | PDPK1 (0.49) | HTR6TNFSF11KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL29714399 | 0.78 | PDPK1 (0.49) | HTR6TNFSF11KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL31211647 | 0.77 | HTR6 (0.77) | HTR6KMT2AL3MBTL1MEN1LMNA | |
| SCHEMBL1172350 | 0.77 | HTR6 (0.77) | HTR6KMT2AL3MBTL1MEN1LMNA | |
| SCHEMBL27641186 | 0.77 | HPGD (0.51) | HTR6TNFSF11KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL1772606 | 0.77 | BRD4 (0.44) | HTR6KMT2AALDH1A1L3MBTL1HTT | |
| SCHEMBL1632297 | 0.76 | HTR6 (0.50) | HTR6TNFSF11KMT2AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979314-B1 | INDOLE SULFONAMIDE MODULATORS OF PROGESTERONE RECEPTORS | LILLY CO ELI (US) | 2013-01-09 | — | — | EP | disclosed |