Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 15/20 | 0.56 |
| ▸ | NAALAD2 | Q9Y3Q0 | 3/20 | 0.56 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14330723 | 0.84 | FOLH1 (0.61) | FOLH1NAALAD2RIMKLASMN1; SMN2 | |
| SCHEMBL13559297 | 0.84 | FOLH1 (0.61) | FOLH1NAALAD2RIMKLASMN1; SMN2 | |
| SCHEMBL14550469 | 0.82 | FOLH1 (0.68) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL19209760 | 0.82 | FOLH1 (0.68) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL12145778 | 0.82 | FOLH1 (0.68) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL22037239 | 0.82 | FOLH1 (0.68) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL10089708 | 0.81 | FOLH1 (0.61) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL14720004 | 0.80 | FOLH1 (0.74) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL14719987 | 0.80 | FOLH1 (0.74) | FOLH1NAALAD2RIMKLA | |
| SCHEMBL13559294 | 0.79 | FOLH1 (0.67) | FOLH1NAALAD2RIMKLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9415113-B2 | Targeting monomers and polymers having targeting blocks | UNIVERSITY OF WASHINGTON (US) | 2016-08-16 | — | — | US | disclosed |
| US-20130011362-A1 | TARGETING MONOMERS AND POLYMERS HAVING TARGETING BLOCKS | PHASERX, INC. (US) | 2013-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130011362-A1 | TARGETING MONOMERS AND POLYMERS HAVING TARGETING BLOCKS | FOLR1, FOLR2, DHFR | FOLH1 14/4885NAALAD2 3927/4885RIMKLA 675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.