SCHEMBL14550425

SCHEMBL14550425

CC(=O)N[C@@H](CO)C(=O)NCCOCCOCCNC(=O)CCCCCCCCCCCCCCCCC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.50
▸ TLR2 O60603 3/20 0.46
▸ NMT2 O60551 1/20 0.43
▸ NMT1 P30419 1/20 0.43
▸ ADRA1A P35348 1/20 0.40
▸ EPHX2 P34913 3/20 0.40
▸ MEN1 O00255 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ SRC P12931 1/20 0.38
▸ EPOR P19235 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13566481 0.83 GLP1R (0.58) GLP1RTLR2ADRA1AMEN1KMT2A
SCHEMBL19465297 0.83 GLP1R (0.58) GLP1RTLR2ADRA1AMEN1KMT2A
SCHEMBL12673824 0.81 ADRA1A (0.61) GLP1RADRA1AEPHX2
SCHEMBL14550117 0.78 GLP1R (0.49) GLP1RTLR2NMT2NMT1
SCHEMBL26257859 0.78 GLP1R (0.63) GLP1RNMT2NMT1EPHX2EPOR
SCHEMBL11921662 0.77 ADRA1A (0.46) GLP1RADRA1AEPHX2
SCHEMBL16167789 0.77 ADRA1A (0.46) GLP1RADRA1AEPHX2
SCHEMBL16167809 0.77 ADRA1A (0.46) GLP1RADRA1AEPHX2
SCHEMBL16167788 0.77 ADRA1A (0.46) GLP1RADRA1AEPHX2
SCHEMBL14118030 0.77 ADRA1A (0.46) GLP1RADRA1AEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130012432-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2013-01-10 — — US disclosed
US-20130012432-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2013-01-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130012432-A1 Peptides for Treatment of Obesity MC4R, GIPR, MC3R GLP1R 5/4885TLR2 1212/4885NMT2 755/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback