Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | GLP1R | P43220 | 8/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14118030 | 1.00 | ADRA1A (0.46) | ADRA1AEPHX2KDM4EGLP1RFAAH | |
| SCHEMBL16167789 | 0.94 | ADRA1A (0.46) | ADRA1AEPHX2KDM4EGLP1RFAAH | |
| SCHEMBL16167788 | 0.94 | ADRA1A (0.46) | ADRA1AEPHX2KDM4EGLP1RFAAH | |
| SCHEMBL11921662 | 0.94 | ADRA1A (0.46) | ADRA1AEPHX2KDM4EGLP1RFAAH | |
| SCHEMBL16167810 | 0.92 | ADRA1A (0.49) | ADRA1AEPHX2KDM4EGLP1RFAAH | |
| SCHEMBL16167786 | 0.92 | ADRA1A (0.49) | ADRA1AEPHX2KDM4EGLP1RFAAH | |
| SCHEMBL16167791 | 0.92 | ADRA1A (0.49) | ADRA1AEPHX2KDM4EGLP1RFAAH | |
| SCHEMBL16167785 | 0.92 | ADRA1A (0.49) | ADRA1AEPHX2KDM4EGLP1RFAAH | |
| SCHEMBL16167792 | 0.92 | ADRA1A (0.49) | ADRA1AEPHX2KDM4EGLP1RFAAH | |
| SCHEMBL14240910 | 0.89 | GLP1R (0.47) | ADRA1AEPHX2KDM4EGLP1RFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8859493-B2 | Insulin derivatives | NOVO NORDISK A/S (DK) | 2014-10-14 | — | — | US | disclosed |