SCHEMBL14550474

SCHEMBL14550474

CC(=O)N[C@@H](CCCCNC(=O)COCCOCCNC(=O)CCCCCCCCCCCCCCCc1nnn[nH]1)C(N)=O

nearest known ligand 0.46

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ ALB P02768 3/20 0.46
▸ GLP1R P43220 8/20 0.44
▸ SIRT5 Q9NXA8 3/20 0.35
▸ CCKAR P32238 4/20 0.34
▸ CCKBR P32239 4/20 0.34
▸ FOLH1 Q04609 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14550481 0.92 GLP1R (0.53) ALBGLP1RCCKARCCKBRFOLH1
SCHEMBL14550401 0.92 GLP1R (0.44) ALBGLP1RCCKARCCKBRFOLH1
SCHEMBL14550491 0.87 GLP1R (0.41) ALBGLP1RSIRT5CCKARCCKBR
SCHEMBL13880505 0.86 GLP1R (0.38) GLP1R
SCHEMBL13880447 0.85 GLP1R (0.42) GLP1RFOLH1
SCHEMBL1286215 0.83 GLP1R (0.36) GLP1R
SCHEMBL14550233 0.82 GLP1R (0.42) GLP1RCCKARCCKBR
SCHEMBL14550528 0.82 GLP1R (0.57) ALBGLP1RSIRT5CCKARCCKBR
SCHEMBL14550527 0.82 GLP1R (0.57) ALBGLP1RSIRT5CCKARCCKBR
SCHEMBL14550140 0.82 GLP1R (0.42) GLP1RCCKARCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130012432-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2013-01-10 — — US disclosed
US-20130012432-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2013-01-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130012432-A1 Peptides for Treatment of Obesity MC4R, GIPR, MC3R ALB 4468/4885GLP1R 5/4885SIRT5 1964/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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