SCHEMBL14550481

SCHEMBL14550481

CC(=O)N[C@@H](CCCCNC(=O)COCCOCCNC(=O)CCCCCCCCCCCCCCCc1nnn[nH]1)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.53
▸ ALB P02768 4/20 0.45
▸ FOLH1 Q04609 6/20 0.40
▸ NOD1 Q9Y239 1/20 0.36
▸ CCKAR P32238 1/20 0.35
▸ CCKBR P32239 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14550474 0.92 ALB (0.46) GLP1RALBFOLH1CCKARCCKBR
SCHEMBL19270361 0.89 GLP1R (0.50) GLP1RALBFOLH1NOD1CCKAR
SCHEMBL16809355 0.89 GLP1R (0.50) GLP1RALBFOLH1NOD1
SCHEMBL24179868 0.89 GLP1R (0.50) GLP1RALBFOLH1NOD1
SCHEMBL23157385 0.89 GLP1R (0.56) GLP1RALBFOLH1NOD1CCKAR
SCHEMBL12673961 0.88 GLP1R (0.53) GLP1RFOLH1NOD1CCKARCCKBR
SCHEMBL12673965 0.88 GLP1R (0.53) GLP1RFOLH1NOD1CCKARCCKBR
SCHEMBL12673959 0.88 GLP1R (0.53) GLP1RFOLH1NOD1CCKARCCKBR
SCHEMBL19243827 0.88 GLP1R (0.53) GLP1RFOLH1NOD1CCKARCCKBR
SCHEMBL15871504 0.88 GLP1R (0.54) GLP1RNOD1CCKARCCKBR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130012432-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2013-01-10 — — US disclosed
US-20130012432-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2013-01-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130012432-A1 Peptides for Treatment of Obesity MC4R, GIPR, MC3R GLP1R 5/4885ALB 4468/4885FOLH1 449/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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