SCHEMBL16809355

SCHEMBL16809355

O=C(CBr)NCCCCC(NC(=O)COCCOCCNC(=O)CCCCCCCCCCCCCCCc1nnn[nH]1)C(=O)O

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.50
▸ FOLH1 Q04609 5/20 0.39
▸ ALB P02768 4/20 0.36
▸ NOD1 Q9Y239 1/20 0.35
▸ GLO1 Q04760 1/20 0.35
▸ C3AR1 Q16581 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20567326 0.92 GLP1R (0.45) GLP1RFOLH1ALB
SCHEMBL20567323 0.92 GLP1R (0.45) GLP1RFOLH1ALB
SCHEMBL28400630 0.92 GLP1R (0.50) GLP1RFOLH1NOD1GLO1
SCHEMBL28400628 0.92 GLP1R (0.50) GLP1RFOLH1NOD1GLO1
SCHEMBL20567466 0.92 GLP1R (0.50) GLP1RFOLH1NOD1GLO1
SCHEMBL20567468 0.92 GLP1R (0.50) GLP1RFOLH1NOD1GLO1
SCHEMBL24179868 0.92 GLP1R (0.50) GLP1RFOLH1ALBNOD1
SCHEMBL19270361 0.92 GLP1R (0.50) GLP1RFOLH1ALBNOD1GLO1
SCHEMBL14550481 0.89 GLP1R (0.53) GLP1RFOLH1ALBNOD1
SCHEMBL15871504 0.89 GLP1R (0.54) GLP1RNOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3079722-B1 METHOD FOR THIOETHER CONJUGATION OF PROTEINS NOVO NORDISK HEALTHCARE AG (CH) 2021-03-24 — — EP disclosed
US-20190203213-A1 Growth Hormones with Prolonged In-Vivo Efficacy NOVO NORDISK HEALTHCARE AG (CH) 2019-07-04 — — US disclosed
US-20170239362-A1 Growth Hormones with Prolonged In-Vivo Efficacy NOVO NORDISK HEALTHCARE AG (CH) 2017-08-24 — — US disclosed
US-9695226-B2 Growth hormones with prolonged in-vivo efficacy NOVO NORDISK HEALTHCARE AG (CH) 2017-07-04 — — US disclosed
US-20160303248-A1 Method for Thioether Conjugation of Proteins NOVO NORDISK HEALTH CARE AG (CH) 2016-10-20 — — US disclosed
WO-2015086853-A1 METHOD FOR THIOETHER CONJUGATION OF PROTEINS NOVO NORDISK HEALTH CARE AG (DK) 2015-06-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160303248-A1 Method for Thioether Conjugation of Proteins TST, P4HB, PDIA6 GLP1R 4417/4885FOLH1 205/4885ALB 77/4885
US-20170239362-A1 Growth Hormones with Prolonged In-Vivo Efficacy SHBG, GHRHR, GHITM GLP1R 101/4885FOLH1 469/4885ALB 15/4885
US-20190203213-A1 Growth Hormones with Prolonged In-Vivo Efficacy SHBG, GHRHR, GHITM GLP1R 101/4885FOLH1 469/4885ALB 15/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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