SCHEMBL14552160

SCHEMBL14552160

CC(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)NCC(=O)N[C@@H](CS)C(=O)N1CCC[C@H]1C

nearest known ligand 0.62

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ CTSL P07711 3/20 0.62
▸ CTSS P25774 3/20 0.62
▸ CTSK P43235 3/20 0.62
▸ CTSH P09668 1/20 0.62
▸ IL23R Q5VWK5 11/20 0.56
▸ MC4R P32245 4/20 0.55
▸ MC5R P33032 2/20 0.55
▸ MC3R P41968 2/20 0.55
▸ MC1R Q01726 2/20 0.55
▸ C5AR1 P21730 1/20 0.54
▸ CXCR4 P61073 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14552592 0.98 CTSL (0.61) CTSLCTSSCTSKCTSHIL23R
SCHEMBL14552163 0.96 CTSL (0.59) CTSLCTSSCTSKCTSHIL23R
SCHEMBL14552164 0.94 CTSL (0.65) CTSLCTSSCTSKCTSHIL23R
SCHEMBL14552136 0.92 CTSL (0.54) CTSLCTSSCTSKCTSHIL23R
SCHEMBL14552192 0.90 CTSL (0.52) CTSLCTSSCTSKCTSHIL23R
SCHEMBL14552191 0.89 CTSL (0.60) CTSLCTSSCTSKCTSHIL23R
SCHEMBL14552142 0.86 IL23R (0.57) IL23RMC4R
SCHEMBL30004418 0.85 IL23R (0.58) IL23R
SCHEMBL23660906 0.85 CTSL (0.65) CTSLCTSSCTSKCTSHIL23R
SCHEMBL23660890 0.85 CTSL (0.65) CTSLCTSSCTSKCTSHIL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130012432-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2013-01-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130012432-A1 Peptides for Treatment of Obesity MC4R, GIPR, MC3R CTSL 717/4885CTSS 1180/4885CTSK 569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback