SCHEMBL14552142

SCHEMBL14552142

CC(=O)N[C@@H](CCS)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CS)C(=O)N1CCC[C@H]1C

nearest known ligand 0.57

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ IL23R Q5VWK5 15/20 0.57
▸ KISS1R Q969F8 3/20 0.52
▸ MC4R P32245 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14552651 0.92 IL23R (0.59) IL23RKISS1RMC4R
SCHEMBL14552136 0.92 CTSL (0.54) IL23RKISS1RMC4R
SCHEMBL14552166 0.90 KISS1R (0.55) IL23RKISS1RMC4R
SCHEMBL14552192 0.89 CTSL (0.52) IL23RKISS1RMC4R
SCHEMBL14552163 0.89 CTSL (0.59) IL23RKISS1RMC4R
SCHEMBL14552592 0.88 CTSL (0.61) IL23RMC4R
SCHEMBL14552817 0.87 IL23R (0.64) IL23RKISS1RMC4R
SCHEMBL14552563 0.86 CXCL8 (0.55) IL23RKISS1RMC4R
SCHEMBL14552160 0.86 CTSL (0.62) IL23RMC4R
SCHEMBL13144542 0.85 IL23R (0.54) IL23RKISS1RMC4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130012432-A1 Peptides for Treatment of Obesity NOVO NORDISK A/S (DK) 2013-01-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130012432-A1 Peptides for Treatment of Obesity MC4R, GIPR, MC3R IL23R 698/4885KISS1R 139/4885MC4R 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback