Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 1/20 | 0.47 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.47 |
| ▸ | SMO | Q99835 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.43 |
| ▸ | TMPRSS4 | Q9NRS4 | 5/20 | 0.42 |
| ▸ | P2RX1 | P51575 | 4/20 | 0.42 |
| ▸ | P2RX4 | Q99571 | 4/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 2/20 | 0.42 |
| ▸ | JAK1 | P23458 | 1/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1455071 | 0.85 | PTGS1 (0.53) | RXFP1PTGS1MEN1ALDH1A1KMT2A | |
| SCHEMBL811386 | 0.81 | PTGS1 (0.59) | RXFP1P2RX1PTGS1MEN1KMT2A | |
| SCHEMBL1456028 | 0.80 | PTGS1 (0.56) | RXFP1P2RX1PTGS1LMNAGAA | |
| SCHEMBL1455344 | 0.79 | NQO2 (0.50) | MEN1ALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL1455121 | 0.78 | MAPT (0.57) | MEN1ALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL1455859 | 0.78 | SNCA (0.50) | AVPR2GPR27ALDH1A1LMNAMAPT | |
| SCHEMBL1455648 | 0.76 | MEN1 (0.52) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL1455186 | 0.76 | MEN1 (0.57) | MEN1ALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL1455484 | 0.76 | ALDH1A1 (0.57) | MEN1ALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL1454847 | 0.76 | DEGS1 (0.49) | JAK2JAK1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1979348-B1 | ANTI-VIRAL COMPOUNDS | ABBOTT LAB (US) | 2012-01-18 | — | — | EP | disclosed |
| US-7910595-B2 | Anti-viral compounds | ABBOTT LABORATORIES (US) | 2011-03-22 | — | — | US | disclosed |
| CN-101384591-A | Antiviral compounds | ABBOTT LAB (US) | 2009-03-11 | — | — | CN | disclosed |
| EP-1979348-A2 | ANTI-VIRAL COMPOUNDS | Abbott Laboratories (US) | 2008-10-15 | — | — | EP | disclosed |
| US-20070232627-A1 | ANTI-VIRAL COMPOUNDS | ABBVIE INC. | 2007-10-04 | — | — | US | disclosed |
| WO-2007076034-A2 | ANTI-VIRAL COMPOUNDS | ABBOTT LABORATORIES (US) | 2007-07-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232627-A1 | ANTI-VIRAL COMPOUNDS | HAVCR2, MAVS, EIF2AK2 | AVPR2 3643/4885GPR27 4746/4885SMO 1597/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.