Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 6/20 | 0.38 |
| ▸ | NOS1 | P29475 | 6/20 | 0.38 |
| ▸ | NOS2 | P35228 | 6/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2981071 | 1.00 | CTSL (0.43) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL24928599 | 0.86 | DPP4 (0.44) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL1584174 | 0.86 | CTSL (0.42) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL6238619 | 0.86 | DPP4 (0.44) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL2981006 | 0.85 | GLB1 (0.41) | CTSLCTSBCTSKOPRM1OPRL1 | |
| Hydrochloric Acid SCHEMBL2146342 | 0.84 | CTSL (0.41) | CTSLCTSBCTSKOPRM1OPRL1 | |
| SCHEMBL19249780 | 0.84 | BCHE (0.52) | CTSLCTSBCTSKBCHEACHE | |
| SCHEMBL27500080 | 0.84 | BCHE (0.52) | CTSLCTSBCTSKBCHEACHE | |
| SCHEMBL13759699 | 0.84 | BCHE (0.52) | CTSLCTSBCTSKBCHEACHE | |
| Methyl Alcohol SCHEMBL27520381 | 0.84 | BCHE (0.49) | BCHEACHENOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013006738-A1 | COMPOUNDS FOR THE TREATMENT OF HIV | GILEAD SCIENCES, INC. (US) | 2013-01-10 | — | — | WO | disclosed |