Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BDKRB2 | P30411 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | NOS3 | P29474 | 6/20 | 0.37 |
| ▸ | NOS1 | P29475 | 6/20 | 0.37 |
| ▸ | NOS2 | P35228 | 6/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6238619 | 1.00 | DPP4 (0.44) | DPP4CTSLCTSBCTSKBCHE | |
| SCHEMBL2981071 | 0.86 | CTSL (0.43) | DPP4CTSLCTSBCTSKBCHE | |
| SCHEMBL14555331 | 0.86 | CTSL (0.43) | DPP4CTSLCTSBCTSKBCHE | |
| SCHEMBL6239011 | 0.85 | IDO1 (0.40) | NOS3NOS1NOS2 | |
| SCHEMBL6236177 | 0.85 | IDO1 (0.40) | NOS3NOS1NOS2 | |
| SCHEMBL1584174 | 0.84 | CTSL (0.42) | DPP4CTSLCTSBCTSKBCHE | |
| SCHEMBL13759699 | 0.83 | BCHE (0.52) | CTSLCTSBCTSKBCHEACHE | |
| SCHEMBL19249780 | 0.83 | BCHE (0.52) | CTSLCTSBCTSKBCHEACHE | |
| Hydrochloric Acid SCHEMBL2146342 | 0.83 | CTSL (0.41) | DPP4CTSLCTSBCTSKBCHE | |
| SCHEMBL27500080 | 0.83 | BCHE (0.52) | CTSLCTSBCTSKBCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009585-A2 | TRANSTHYRETIN STABILIZING COMPOUNDS | PROTEGO BIOPHARMA, INC. (US) | 2023-02-02 | — | — | WO | disclosed |