SCHEMBL14557129

SCHEMBL14557129

c1ccc2c(c1)-c1ccccc1N(c1ccc(N3c4ccccc4-c4ccccc4-c4ccccc43)s1)c1ccccc1-2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES1 P23141 4/20 0.36
CES2 O00748 2/20 0.36
BCHE P06276 2/20 0.36
NPSR1 Q6W5P4 2/20 0.36
ALDH1A1 P00352 2/20 0.36
MGLL Q99685 1/20 0.36
GAA P10253 1/20 0.36
DNMT1 P26358 1/20 0.34
RAD52 P43351 1/20 0.34
UHRF1 Q96T88 1/20 0.34
GPR3 P46089 1/20 0.32
NR1H2 P55055 1/20 0.32
POLB P06746 2/20 0.31
TLR9 Q9NR96 1/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
KDM4E B2RXH2 1/20 0.31
APAF1 O14727 1/20 0.31
TERT O14746 1/20 0.31
NPC1 O15118 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14557134 0.87 APP (0.34) CES1CES2BCHENPSR1ALDH1A1
SCHEMBL19603607 0.76 MAPT (0.56) CES1CES2BCHENPSR1ALDH1A1
SCHEMBL10013271 0.72 ALDH1A1 (0.50) CES1CES2BCHENPSR1ALDH1A1
SCHEMBL64821 0.70 CES1 (0.43) CES1CES2BCHENPSR1ALDH1A1
SCHEMBL12320704 0.70 ALDH1A1 (0.59) CES1CES2BCHENPSR1ALDH1A1
SCHEMBL19602228 0.70 ALDH1A1 (0.59) CES1CES2BCHENPSR1ALDH1A1
SCHEMBL13314104 0.70 CES1 (0.39) CES1CES2BCHENPSR1ALDH1A1
SCHEMBL13231527 0.70 KMT2A (0.41) NPSR1ALDH1A1GAAPOLBMEN1
SCHEMBL13941880 0.70 MGLL (0.39) CES1CES2BCHENPSR1ALDH1A1
SCHEMBL14557127 0.68 POLB (0.50) CES1CES2BCHENPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070052051-A1 Photoelectric conversion layer, photoelectric conversion device and imaging device, and method for applying electric field thereto FUJI PHOTO FILM CO., LTD. 2007-03-08 US disclosed
US-20070052051-A1 Photoelectric conversion layer, photoelectric conversion device and imaging device, and method for applying electric field thereto FUJI PHOTO FILM CO., LTD. 2007-03-08 US disclosed