Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PHLPP2 | Q6ZVD8 | 3/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.36 |
| ▸ | SENP2 | Q9HC62 | 3/20 | 0.34 |
| ▸ | SUMO2 | P61956 | 2/20 | 0.34 |
| ▸ | SUMO1 | P63165 | 2/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | STAT6 | P42226 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CD40 | P25942 | 1/20 | 0.33 |
| ▸ | CD40LG | P29965 | 1/20 | 0.33 |
| ▸ | SENP3 | Q9H4L4 | 2/20 | 0.30 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14565614 | 0.86 | ENPP2 (0.45) | THRBPHLPP2ENPP2SENP2SUMO2 | |
| SCHEMBL24019203 | 0.83 | THRB (0.45) | THRBPHLPP2ENPP2SENP2SUMO2 | |
| SCHEMBL17384289 | 0.80 | THRB (0.45) | THRBPHLPP2ENPP2SENP2SUMO2 | |
| SCHEMBL14159105 | 0.78 | PHLPP2 (0.53) | THRBPHLPP2ENPP2SENP2SUMO2 | |
| SCHEMBL14159099 | 0.78 | THRB (0.43) | THRBPHLPP2ENPP2SENP2SUMO2 | |
| SCHEMBL14547026 | 0.78 | THRB (0.43) | THRBPHLPP2ENPP2SENP2SUMO2 | |
| SCHEMBL14159117 | 0.78 | PHLPP2 (0.52) | THRBPHLPP2ENPP2SENP2SUMO2 | |
| SCHEMBL13387274 | 0.78 | THRB (0.34) | THRBPHLPP2ENPP2 | |
| SCHEMBL12052542 | 0.77 | THRB (0.31) | THRBPHLPP2ENPP2 | |
| SCHEMBL24019208 | 0.77 | PHLPP2 (0.42) | THRBPHLPP2ENPP2CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1760117-A2 | Reactive dyestuff compositions and their use | Everlight USA, Inc. (US) | 2007-03-07 | — | — | EP | disclosed |
| US-20070044256-A1 | Reactive dyestuff composition and their use | EVERLIGHT USA, INC. (US) | 2007-03-01 | — | — | US | disclosed |