Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.39 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31650430 | 0.82 | ALDH1A1 (0.46) | ALDH1A1KMT2AMAPTKDM4EGAA | |
| SCHEMBL5339440 | 0.82 | GAA (0.42) | ALDH1A1DRD2HTR2AMAPTGAA | |
| SCHEMBL5027897 | 0.81 | ALDH1A1 (0.45) | ALDH1A1KMT2AMAPTKDM4EGAA | |
| SCHEMBL30759564 | 0.81 | MAPT (0.45) | ALDH1A1KMT2AMAPTKDM4EGAA | |
| SCHEMBL27120697 | 0.81 | MAPT (0.45) | ALDH1A1KMT2AMAPTKDM4EGAA | |
| SCHEMBL31650408 | 0.81 | ALDH1A1 (0.45) | ALDH1A1KMT2AMAPTKDM4EGAA | |
| SCHEMBL14558824 | 0.81 | KMT2A (0.43) | ALDH1A1KMT2AMAPTGAAMEN1 | |
| SCHEMBL31650300 | 0.81 | CYP19A1 (0.48) | ALDH1A1KMT2AMAPTKDM4EGAA | |
| SCHEMBL31650126 | 0.78 | ACHE (0.51) | ALDH1A1KMT2AMAPTKDM4EGAA | |
| SCHEMBL1160244 | 0.78 | ACHE (0.51) | ALDH1A1KMT2AMAPTKDM4EGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186743-B2 | Substituted pyrazolyl compounds for the treatment of inflammation | PHARMACIA CORPORATION (US) | 2007-03-06 | — | — | US | disclosed |
| US-7186743-B2 | Substituted pyrazolyl compounds for the treatment of inflammation | PHARMACIA CORPORATION (US) | 2007-03-06 | — | — | US | disclosed |