Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.42 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14558294 | 0.86 | DPP4 (0.51) | KDM4ELMNAHPGDKMT2APOLB | |
| SCHEMBL8295004 | 0.83 | KDM4E (0.50) | KDM4ELMNAHPGDKMT2ANPC1 | |
| SCHEMBL2237253 | 0.82 | KDM4E (0.59) | KDM4ELMNAHPGDKMT2ANPC1 | |
| SCHEMBL2237243 | 0.82 | KDM4E (0.59) | KDM4ELMNAHPGDKMT2ANPC1 | |
| SCHEMBL5708852 | 0.80 | DPP4 (0.54) | DPP7DPP4DPP8DPP9 | |
| SCHEMBL14558290 | 0.77 | DPP4 (0.57) | DPP7DPP4DPP8DPP9 | |
| SCHEMBL30880806 | 0.77 | KDM4E (0.52) | KDM4ELMNAHPGDKMT2ANPC1 | |
| SCHEMBL26922222 | 0.76 | DRD2 (0.61) | KDM4EKMT2ANPC1ALOX15RAB9A | |
| SCHEMBL30880800 | 0.76 | KDM4E (0.51) | KDM4ELMNAHPGDKMT2ANPC1 | |
| Trifluoroacetic Acid SCHEMBL6821632 | 0.75 | DPP4 (0.55) | DPP7DPP4DPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189728-B2 | Inhibitors of dipeptidyl peptidase IV | FERRING, BV (NL) | 2007-03-13 | — | — | US | disclosed |
| US-7189728-B2 | Inhibitors of dipeptidyl peptidase IV | FERRING, BV (NL) | 2007-03-13 | — | — | US | disclosed |