Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | OTC | P00480 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2237253 | 1.00 | KDM4E (0.59) | KDM4ELMNAHPGDKMT2AMEN1 | |
| SCHEMBL2236090 | 0.92 | HPGD (0.65) | KDM4ELMNAHPGDKMT2AMEN1 | |
| SCHEMBL2236078 | 0.92 | HPGD (0.65) | KDM4ELMNAHPGDKMT2AMEN1 | |
| SCHEMBL2240076 | 0.83 | HPGD (0.53) | KDM4ELMNAHPGDKMT2AMEN1 | |
| SCHEMBL15209459 | 0.83 | HPGD (0.53) | KDM4ELMNAHPGDKMT2AMEN1 | |
| SCHEMBL14558293 | 0.82 | KDM4E (0.51) | KDM4ELMNAHPGDKMT2AMEN1 | |
| SCHEMBL25146755 | 0.82 | KDM4E (0.68) | KDM4ELMNAHPGDKMT2AMEN1 | |
| SCHEMBL2240238 | 0.81 | SMN1; SMN2 (0.63) | KMT2AMEN1HDAC3HDAC1SMN1; SMN2 | |
| SCHEMBL2240242 | 0.81 | SMN1; SMN2 (0.63) | KMT2AMEN1HDAC3HDAC1SMN1; SMN2 | |
| SCHEMBL5965431 | 0.80 | KDM4E (0.47) | KDM4ELMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109400-B | Biodegradable butylene glycol-based polyester elastomer tread rubber and preparation method thereof | 北京化工大学 | 2025-04-29 | — | — | CN | disclosed |
| CN-119173562-A | Process for recovering raw materials from isocyanurate-containing polyurethane products | 科思创德国股份有限公司 | 2024-12-20 | — | — | CN | disclosed |
| CN-115109401-B | Polyester rubber composite tire with biodegradable tread and preparation method thereof | 北京化工大学 | 2024-10-11 | — | — | CN | disclosed |
| CN-118339223-A | Method for recovering raw materials from polyurethane products | 科思创德国股份有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-118215707-A | Method for recovering raw materials from polyurethane products | 科思创德国股份有限公司 | 2024-06-18 | — | — | CN | disclosed |
| CN-113993928-B | Method for recovering raw materials from polyurethane products | 科思创德国股份有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-118139918-A | Method for cleaving (poly) urethanes | 科思创德国股份有限公司 | 2024-06-04 | — | — | CN | disclosed |
| CN-115109399-B | Degradable sole and welt rubber material, and preparation method and application thereof | 北京化工大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-117480207-A | Method for cracking polyurethane products | 科思创德国股份有限公司 | 2024-01-30 | — | — | CN | disclosed |
| US-11793855-B2 | TFPI inhibitors and methods of use | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2023-10-24 | — | — | US | disclosed |
| WO-2013141965-A1 | TFPI INHIBITORS AND METHODS OF USE | BAXTER INTERNATIONAL INC. (US) | 2013-09-26 | — | — | WO | disclosed |
| US-20130252896-A1 | TFPI INHIBITORS AND METHODS OF USE | BAXTER HEALTHCARE SA (CH) | 2013-09-26 | — | — | US | disclosed |
| US-20130225506-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CXCR7 MODULATING ACTIVITY | POLYPHOR AG (CH) | 2013-08-29 | — | — | US | disclosed |
| US-8450275-B2 | TFPI inhibitors and methods of use | BAXTER INTERNATIONAL INC. (US) | 2013-05-28 | — | — | US | disclosed |
| US-8450275-B2 | TFPI inhibitors and methods of use | BAXTER INTERNATIONAL INC. (US) | 2013-05-28 | — | — | US | disclosed |
| EP-2531520-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CXCR7 MODULATING ACTIVITY | Polyphor AG (CH) | 2012-12-12 | — | — | EP | disclosed |
| US-20120028901-A1 | TFPI INHIBITORS AND METHODS OF USE | BAXTER INTERNATIONAL INC. (US) | 2012-02-02 | — | — | US | disclosed |
| US-20120028901-A1 | TFPI INHIBITORS AND METHODS OF USE | BAXTER INTERNATIONAL INC. (US) | 2012-02-02 | — | — | US | disclosed |
| WO-2011115712-A2 | TFPI INHIBITORS AND METHODS OF USE | BAXTER INTERNATIONAL INC (US) | 2011-09-22 | — | — | WO | disclosed |
| WO-2011095607-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CXCR7 MODULATING ACTIVITY | POLYPHOR AG (CH) | 2011-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120028901-A1 | TFPI INHIBITORS AND METHODS OF USE | TFPI, TFPI2, F3 | KDM4E 4344/4885LMNA 1445/4885HPGD 1796/4885 |
| US-20130252896-A1 | TFPI INHIBITORS AND METHODS OF USE | TFPI, TFPI2, F13B | KDM4E 4610/4885LMNA 1505/4885HPGD 1650/4885 |
| US-11793855-B2 | TFPI inhibitors and methods of use | TFPI, TFPI2, F3 | KDM4E 4324/4885LMNA 1466/4885HPGD 1870/4885 |
| US-20130225506-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CXCR7 MODULATING ACTIVITY | CXCR1, CXCL12, CXCR6 | KDM4E 4606/4885LMNA 4127/4885HPGD 2044/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.