SCHEMBL1455840

SCHEMBL1455840

Cc1ccc(N(c2ccccc2)c2c3ccccc3c(N(c3ccccc3)c3ccc(C)c4ccccc34)c3ccccc23)c2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.48
CYP2A6 P11509 3/20 0.38
ALDH1A1 P00352 2/20 0.33
CHEK1 O14757 1/20 0.32
NEK2 P51955 1/20 0.32
LIMK1 P53667 1/20 0.32
DYRK1A Q13627 1/20 0.32
CLK4 Q9HAZ1 1/20 0.32
KDM4E B2RXH2 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32
MAPT P10636 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
GRIN2D O15399 1/20 0.32
GRIN3B O60391 1/20 0.32
GRIN1 Q05586 1/20 0.32
GRIN2A Q12879 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17879379 0.95 CYP1A2 (0.43) CYP1A2CYP2A6ALDH1A1CHEK1NEK2
SCHEMBL10053533 0.90 CYP1A2 (0.54) CYP1A2CYP2A6ALDH1A1CHEK1NEK2
SCHEMBL12394113 0.90 CYP1A2 (0.54) CYP1A2CYP2A6ALDH1A1CHEK1NEK2
SCHEMBL19660700 0.85 CYP1A2 (0.48) CYP1A2CYP2A6ALDH1A1CHEK1NEK2
SCHEMBL17879387 0.85 CYP1A2 (0.41) CYP1A2CYP2A6ALDH1A1CYP2C19TSHR
SCHEMBL13868380 0.84 CYP1A2 (0.46) CYP1A2CYP2A6ALDH1A1CHEK1NEK2
SCHEMBL1455714 0.84 CYP1A2 (0.46) CYP1A2CYP2A6ALDH1A1CHEK1NEK2
SCHEMBL13948910 0.84 CYP2C19 (0.38) CYP1A2ALDH1A1CHEK1NEK2LIMK1
SCHEMBL14018317 0.82 CYP1A2 (0.45) CYP1A2CYP2A6ALDH1A1CHEK1NEK2
SCHEMBL12262924 0.82 CYP1A2 (0.45) CYP1A2CYP2A6ALDH1A1CHEK1NEK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7910687-B2 Conjugated polymers containing arylamine units, the representation thereof and the use of the same MERCK PATENT GMBH (DE) 2011-03-22 US disclosed
EP-1558662-B1 CONJUGATED POLYMERS CONTAINING ARYLAMINE UNITS, THE REPRESENTATION THEREOF AND THE USE OF THE SAME MERCK PATENT GMBH (DE) 2006-12-13 EP disclosed
US-20060058494-A1 Conjugated polymers containing arylamine units, the representation thereof and the use of the same CONVION ORGANIC SEMICONDUCTORS GMBH INTELLECTUAL PROPERTY GROUP (DE) 2006-03-16 US disclosed
EP-1558662-A2 CONJUGATED POLYMERS CONTAINING ARYLAMINE UNITS, THE REPRESENTATION THEREOF AND THE USE OF THE SAME Covion Organic Semiconductors GmbH (DE) 2005-08-03 EP disclosed
WO-2004037887-A2 CONJUGATED POLYMERS CONTAINING ARYLAMINE UNITS, THE REPRESENTATION THEREOF AND THE USE OF THE SAME COVION ORGANIC SEMICONDUCTORS GMBH (DE) 2004-05-06 WO disclosed