SCHEMBL19660700

SCHEMBL19660700

Cc1ccc(-c2ccc(N(c3ccccc3)c3ccccc3)c3ccccc23)c2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.48
CYP2A6 P11509 3/20 0.38
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36
MAPT P10636 3/20 0.35
KDM4E B2RXH2 3/20 0.35
PABPC1 P11940 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
SLC22A12 Q96S37 1/20 0.34
ALDH1A1 P00352 4/20 0.33
HPGD P15428 3/20 0.33
LMNA P02545 1/20 0.33
MAPK1 P28482 1/20 0.33
CHEK1 O14757 1/20 0.32
NEK2 P51955 1/20 0.32
LIMK1 P53667 1/20 0.32
DYRK1A Q13627 1/20 0.32
CLK4 Q9HAZ1 1/20 0.32
CYP3A4 P08684 1/20 0.32
CYP2D6 P10635 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12394113 0.94 CYP1A2 (0.54) CYP1A2CYP2A6RXRARXRBMAPT
SCHEMBL13908268 0.91 CYP1A2 (0.43) CYP1A2CYP2A6RXRARXRBMAPT
SCHEMBL10053533 0.90 CYP1A2 (0.54) CYP1A2CYP2A6MAPTKDM4ESMN1; SMN2
SCHEMBL12031841 0.88 ALDH1A1 (0.39) CYP1A2RXRARXRBMAPTKDM4E
SCHEMBL10128609 0.88 ALDH1A1 (0.39) CYP1A2RXRARXRBMAPTKDM4E
SCHEMBL7214261 0.88 ALDH1A1 (0.39) CYP1A2RXRARXRBMAPTKDM4E
SCHEMBL1455714 0.87 CYP1A2 (0.46) CYP1A2CYP2A6RXRARXRBMAPT
SCHEMBL13868380 0.87 CYP1A2 (0.46) CYP1A2CYP2A6MAPTKDM4EALDH1A1
SCHEMBL12262924 0.86 CYP1A2 (0.45) CYP1A2CYP2A6MAPTKDM4ESMN1; SMN2
SCHEMBL14018317 0.86 CYP1A2 (0.45) CYP1A2CYP2A6RXRARXRBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017204556-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME AND ELECTRONIC DEVICE THEREFOR 덕산네오룩스 주식회사 2017-11-30 WO disclosed