Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA1 | P00915 | 3/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.49 |
| ▸ | CA9 | Q16790 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.47 |
| ▸ | PTPRF | P10586 | 2/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | IDE | P14735 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14563129 | 0.88 | F2 (0.45) | PKMCA12CA1CA2CA9 | |
| SCHEMBL5903487 | 0.84 | TDP1 (0.65) | PKMCA12CA1CA2CA9 | |
| SCHEMBL20068708 | 0.84 | TDP1 (0.65) | PKMCA12CA1CA2CA9 | |
| SCHEMBL5903492 | 0.78 | TDP1 (0.55) | PKMCA12CA1CA2CA9 | |
| SCHEMBL14563108 | 0.77 | TDP1 (0.50) | PKMCA12CA1CA2CA9 | |
| SCHEMBL5903549 | 0.76 | TDP1 (0.48) | PKMCA12CA1CA2CA9 | |
| SCHEMBL28659111 | 0.76 | CA12 (0.72) | PKMCA12CA1CA2CA9 | |
| SCHEMBL29459191 | 0.76 | CA12 (0.72) | PKMCA12CA1CA2CA9 | |
| SCHEMBL18760076 | 0.76 | FOLH1 (0.53) | PKMTDP1FOLH1MEN1ABL1 | |
| SCHEMBL21361156 | 0.75 | TDP1 (0.64) | PKMCA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8951499-B2 | Trifunctional reagent for conjugation to a biomolecule | UNIVERSITY OF WASHINGTON (US) | 2015-02-10 | — | — | US | disclosed |
| US-8951499-B2 | Trifunctional reagent for conjugation to a biomolecule | UNIVERSITY OF WASHINGTON (US) | 2015-02-10 | — | — | US | disclosed |
| US-20070071673-A1 | Trifunctional reagent for conjugation to a biomolecule | MITRA MEDICAL TECHNOLOGY AB (SE) | 2007-03-29 | — | — | US | disclosed |
| US-20070071673-A1 | Trifunctional reagent for conjugation to a biomolecule | MITRA MEDICAL TECHNOLOGY AB (SE) | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070071673-A1 | Trifunctional reagent for conjugation to a biomolecule | UACA, TNFSF11, CD40 | PKM 3320/4885CA12 2857/4885CA1 2939/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.