Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.48 |
| ▸ | PKM | P14618 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | IDE | P14735 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.45 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 4/20 | 0.45 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | CA9 | Q16790 | 4/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14563108 | 0.92 | TDP1 (0.50) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL318637 | 0.86 | TDP1 (0.61) | TDP1PKMMEN1ABL1LMNA | |
| Biotin SCHEMBL4360688 | 0.83 | TDP1 (0.64) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL5903487 | 0.82 | TDP1 (0.65) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL20068708 | 0.82 | TDP1 (0.65) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL14563129 | 0.82 | F2 (0.45) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL5903492 | 0.81 | TDP1 (0.55) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL13790958 | 0.79 | TDP1 (0.56) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL318962 | 0.78 | TDP1 (0.53) | TDP1PKMMEN1ABL1LMNA | |
| SCHEMBL29392244 | 0.77 | PRSS1 (0.64) | TDP1PKMF2PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7141676-B1 | Water soluble multi-biotin-containing compounds | UNIVERSITY OF WASHINGTON (US) | 2006-11-28 | — | — | US | disclosed |
| US-20060228325-A1 | Water soluble multi-biotin-containing compounds | WILBUR D S | 2006-10-12 | — | — | US | disclosed |
| EP-1196199-A4 | WATER SOLUBLE MULTI-BIOTIN-CONTAINING COMPOUNDS | UNIV WASHINGTON (US) | 2002-06-19 | — | — | EP | disclosed |
| EP-1196199-A2 | WATER SOLUBLE MULTI-BIOTIN-CONTAINING COMPOUNDS | University of Washington (US) | 2002-04-17 | — | — | EP | disclosed |
| WO-2000072802-A2 | WATER SOLUBLE MULTI-BIOTIN-CONTAINING COMPOUNDS | UNIVERSITY OF WASHINGTON (US) | 2000-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060228325-A1 | Water soluble multi-biotin-containing compounds | BTD, HLCS, VNN1 | TDP1 2706/4885PKM 4073/4885MEN1 3462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.