Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 4/20 | 0.41 |
| ▸ | CD74 | P04233 | 2/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 6/20 | 0.37 |
| ▸ | BCHE | P06276 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | BRAF | P15056 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CBX7 | O95931 | 1/20 | 0.36 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.36 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.36 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14563146 | 0.94 | MIF (0.43) | MIFCD74ALDH1A1LMNATSHR | |
| SCHEMBL2541369 | 0.86 | TP53 (0.49) | MIFALDH1A1LMNATP53 | |
| SCHEMBL3665095 | 0.81 | MIF (0.51) | MIFCD74ALDH1A1LMNATSHR | |
| SCHEMBL3663233 | 0.80 | MIF (0.48) | MIFCD74ALDH1A1LMNATSHR | |
| SCHEMBL2542481 | 0.79 | TP53 (0.52) | MIFALDH1A1LMNATP53 | |
| SCHEMBL2546842 | 0.74 | MAPT (0.50) | MIFCD74ALDH1A1LMNATSHR | |
| SCHEMBL3631378 | 0.73 | ACHE (0.48) | MIFCD74ACHEBCHE | |
| SCHEMBL2544424 | 0.71 | MAPT (0.49) | MIFCD74TP53 | |
| SCHEMBL3633760 | 0.71 | ACHE (0.43) | MIFCD74ACHEBCHE | |
| SCHEMBL3627312 | 0.69 | MET (0.40) | FAAHACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2150551-B1 | 2-OXO-3-BENZYL-BENZOXAZOL-2-ONE DERIVATIVES AND RELATED COMPOUNDS AS MET KINASE INHIBITORS FOR THE TREATMENT OF TUMORS | MERCK PATENT GMBH (DE) | 2013-01-16 | — | — | EP | claimed |
| EP-2150551-B1 | 2-OXO-3-BENZYL-BENZOXAZOL-2-ONE DERIVATIVES AND RELATED COMPOUNDS AS MET KINASE INHIBITORS FOR THE TREATMENT OF TUMORS | MERCK PATENT GMBH (DE) | 2013-01-16 | — | — | EP | disclosed |