Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 13/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16092996 | 1.00 | MAOA (0.48) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL13921052 | 0.75 | MAOA (0.50) | MAOAKCNH2 | |
| SCHEMBL3325038 | 0.75 | MAOA (0.60) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL18402991 | 0.75 | CYP3A4 (0.41) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL5235825 | 0.75 | MAOA (0.57) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL5239547 | 0.74 | MAOA (0.56) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL5237207 | 0.74 | MAOA (0.53) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL21217536 | 0.73 | GAA (0.41) | — | |
| SCHEMBL11983302 | 0.73 | MAOA (0.73) | MAOAMAOBCYP3A4CYP2D6KCNH2 | |
| SCHEMBL21999224 | 0.73 | MAOA (0.67) | MAOAMAOBCYP3A4CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070072811-A1 | Bifunctional heterocyclic compounds and methods of making and using the same | RIB-X PHARMACEUTICALS, INC. | 2007-03-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072811-A1 | Bifunctional heterocyclic compounds and methods of making and using the same | PCNA, DCX, HPGDS | MAOA 655/4885MAOB 794/4885CYP3A4 1537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.