SCHEMBL1456476

SCHEMBL1456476

CCCCCCCCCCCCCCCCCC(=O)NC1CCCCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.75
HDAC3 O15379 2/20 0.69
HDAC1 Q13547 2/20 0.69
HDAC2 Q92769 2/20 0.69
HDAC10 Q969S8 2/20 0.69
HDAC11 Q96DB2 2/20 0.69
HDAC8 Q9BY41 2/20 0.69
HDAC6 Q9UBN7 2/20 0.69
NCOR2 Q9Y618 1/20 0.69
GNAI3 P08754 1/20 0.69
GNAO1 P09471 1/20 0.69
GNAI1 P63096 1/20 0.69
EPHX1 P07099 9/20 0.61
EPHX2 P34913 2/20 0.61
ALDH1A1 P00352 1/20 0.58
TRPV1 Q8NER1 2/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14520558 1.00 SMN1; SMN2 (0.75) SMN1; SMN2HDAC3HDAC1HDAC2HDAC10
SCHEMBL12196021 1.00 SMN1; SMN2 (0.75) SMN1; SMN2HDAC3HDAC1HDAC2HDAC10
SCHEMBL28519164 1.00 SMN1; SMN2 (0.75) SMN1; SMN2HDAC3HDAC1HDAC2HDAC10
SCHEMBL5002618 1.00 SMN1; SMN2 (0.75) SMN1; SMN2HDAC3HDAC1HDAC2HDAC10
Hexadecanoic Acid Cyclohexylamide SCHEMBL1456860 1.00 SMN1; SMN2 (0.75) SMN1; SMN2HDAC3HDAC1HDAC2HDAC10
SCHEMBL30590541 1.00 SMN1; SMN2 (0.75) SMN1; SMN2HDAC3HDAC1HDAC2HDAC10
SCHEMBL11080983 1.00 SMN1; SMN2 (0.75) SMN1; SMN2HDAC3HDAC1HDAC2HDAC10
SCHEMBL21443012 1.00 SMN1; SMN2 (0.75) SMN1; SMN2HDAC3HDAC1HDAC2HDAC10
SCHEMBL21442874 1.00 SMN1; SMN2 (0.75) SMN1; SMN2HDAC3HDAC1HDAC2HDAC10
SCHEMBL27622463 1.00 SMN1; SMN2 (0.75) SMN1; SMN2HDAC3HDAC1HDAC2HDAC10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59002886-A None JP disclosed
CN-112358415-A Gel factor for curing organic waste liquid at normal temperature and preparation method thereof 中北大学 2021-02-12 CN disclosed
EP-1592418-B1 USE OF ENDOCANNABINOID-LIKE COMPOUNDS FOR TREATING CNS DEGENERATIVE DISORDERS RES & INNOVATION S P A (IT) 2017-09-06 EP disclosed
US-20130190502-A1 ACYLATION REACTION OF HYDROXYL GROUP TAKASAGO INTERNATIONAL CORPORATION (JP) 2013-07-25 US disclosed
US-8431709-B2 Acylation reaction of hydroxyl group TAKASAGO INTERNATIONAL CORPORATION (JP) 2013-04-30 US disclosed
EP-1900365-B9 Endocannabinoid-like compounds and their use for treating dermatitis RES & INNOVATION S P A (IT) 2012-01-18 EP disclosed
EP-1900365-B1 Endocannabinoid-like compounds and their use for treating dermatitis RES & INNOVATION S P A (IT) 2011-03-30 EP disclosed
US-20100249422-A1 ACYLATION REACTION OF HYDROXYL GROUP TAKASAGO INTERNATIONAL CORPORATION (JP) 2010-09-30 US disclosed
EP-1900365-A2 New endocannabinoid-like compounds and their use RESEARCH & INNOVATION SOC. COOP. A R.L. (IT) 2008-03-19 EP disclosed
EP-1592418-A2 USE IN THERAPY OF ENDOCANNABINOID-LIKE COMPOUNDS Research & Innovation Soc. Coop. A R.L. (IT) 2005-11-09 EP disclosed
US-4587537-A WAX, A TEREPHTHALATE, BENZYL P-HYDROXYBENZOATE DEVELOPER MITSUBISHI PAPER MILLS, LTD. (JP) 1986-05-06 US disclosed
US-4575734-A LEVCO DYES RICOH COMPANY, LTD. (JP) 1986-03-11 US disclosed
US-4562448-A Heat-sensitive transfer medium RICOH CO., LTD. (JP) 1985-12-31 US disclosed
US-4547788-A SHEET HAVING LAYER CONTAINING LEVCO DYE; ACCEPTOR SHEET CONTAININGCOLORING AGENT; POROUS FILLER RICOH COMPANY, LTD. (JP) 1985-10-15 US disclosed
US-4538164-A LEUCO DYE, HYDROXYPHENOLIC ETHER DEVELOPER, OIL ABSORBING FILLER RICOH CO., LTD. (JP) 1985-08-27 US disclosed
US-4500896-A Heat-sensitive recording medium affording patterns with different colors RICOH COMPANY, LTD. (JP) 1985-02-19 US disclosed
US-4462926-A CYCLOHEXYL AMIDES OF FATTY ACIDS AND POLYESTERAMIDES BAYER AKTIENGESELLSCHAFT (DE) 1984-07-31 US disclosed
JP-S592886-A DIAZO-BASED HEAT-SENSITIVE RECORDING MATERIAL RICOH CO LTD 1984-01-09 JP disclosed
US-4352860-A Thermosensitive recording material RICOH COMPANY, LTD. (JP) 1982-10-05 US disclosed
US-3989677-A STEAM, WATER BAYER AKTIENGESELLSCHAFT (DT) 1976-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130190502-A1 ACYLATION REACTION OF HYDROXYL GROUP ADH5, ADH1A, ACADM SMN1; SMN2 4601/4885HDAC3 243/4885HDAC1 229/4885
US-20100249422-A1 ACYLATION REACTION OF HYDROXYL GROUP ADH5, ADH1A, ACADM SMN1; SMN2 4601/4885HDAC3 243/4885HDAC1 229/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.