Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.68 |
| ▸ | FAAH | O00519 | 7/20 | 0.62 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.59 |
| ▸ | CASP2 | P42575 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | NAAA | Q02083 | 1/20 | 0.55 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.51 |
| ▸ | SELP | P16109 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1456865 | 1.00 | CNR1 (0.68) | CNR1FAAHDNM1CASP2MEN1 | |
| SCHEMBL1695972 | 1.00 | CNR1 (0.68) | CNR1FAAHDNM1CASP2MEN1 | |
| SCHEMBL5866922 | 1.00 | CNR1 (0.68) | CNR1FAAHDNM1CASP2MEN1 | |
| SCHEMBL17125686 | 0.98 | CNR1 (0.69) | CNR1FAAHDNM1CASP2MEN1 | |
| SCHEMBL8847697 | 0.92 | CNR1 (0.67) | CNR1FAAHDNM1CASP2MEN1 | |
| SCHEMBL24415817 | 0.91 | FAAH (0.61) | CNR1FAAHDNM1CASP2MEN1 | |
| SCHEMBL16619882 | 0.91 | CNR1 (0.84) | CNR1MEN1KMT2ALPAR2EPHX2 | |
| SCHEMBL26044981 | 0.91 | CNR1 (0.84) | CNR1MEN1KMT2ALPAR2EPHX2 | |
| SCHEMBL16619880 | 0.91 | CNR1 (0.84) | CNR1MEN1KMT2ALPAR2EPHX2 | |
| SCHEMBL24810920 | 0.89 | CASP2 (0.65) | CNR1FAAHDNM1CASP2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1592418-B1 | USE OF ENDOCANNABINOID-LIKE COMPOUNDS FOR TREATING CNS DEGENERATIVE DISORDERS | RES & INNOVATION S P A (IT) | 2017-09-06 | — | — | EP | disclosed |
| EP-1900365-B9 | Endocannabinoid-like compounds and their use for treating dermatitis | RES & INNOVATION S P A (IT) | 2012-01-18 | — | — | EP | disclosed |
| EP-1900365-B1 | Endocannabinoid-like compounds and their use for treating dermatitis | RES & INNOVATION S P A (IT) | 2011-03-30 | — | — | EP | disclosed |
| EP-1900365-A2 | New endocannabinoid-like compounds and their use | RESEARCH & INNOVATION SOC. COOP. A R.L. (IT) | 2008-03-19 | — | — | EP | disclosed |
| EP-1592418-A2 | USE IN THERAPY OF ENDOCANNABINOID-LIKE COMPOUNDS | Research & Innovation Soc. Coop. A R.L. (IT) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004069240-A2 | USE IN THERAPY OF ENDOCANNABINOID-LIKE COMPOUNDS | RESEARCH & INNOVATION SOC. COOP. A. R. L. (IT) | 2004-08-19 | — | — | WO | disclosed |