Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGT | O15294 | 1/20 | 0.50 |
| ▸ | NOS1 | P29475 | 1/20 | 0.49 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14565145 | 0.88 | OGT (0.50) | OGTNOS1GRIN2BPOLBPDE3B | |
| SCHEMBL5472766 | 0.83 | NOS1 (0.55) | OGTNOS1GRIN2BALDH1A1CREBBP | |
| SCHEMBL17261397 | 0.83 | CREBBP (0.50) | NOS1POLBALDH1A1CREBBPKDM4E | |
| SCHEMBL14565105 | 0.83 | NOS1 (0.51) | OGTNOS1GRIN2BALDH1A1CREBBP | |
| SCHEMBL8697217 | 0.82 | PSMB8 (0.50) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL2547913 | 0.80 | NOS1 (0.57) | OGTNOS1GRIN2BPOLBALDH1A1 | |
| SCHEMBL22382321 | 0.79 | NOS1 (0.49) | OGTNOS1GRIN2BPOLBALDH1A1 | |
| SCHEMBL4135866 | 0.76 | NOS1 (0.53) | OGTNOS1POLBALDH1A1CREBBP | |
| SCHEMBL9909873 | 0.76 | NOS1 (0.61) | OGTNOS1POLBALDH1A1CREBBP | |
| Hydrochloric Acid SCHEMBL10538242 | 0.75 | NOS1 (0.47) | OGTNOS1GRIN2BPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070054899-A1 | Aromatase inhibitor compounds and uses thereof | PARALLEL WIRELESS, INC. | 2007-03-08 | — | — | US | disclosed |
| US-20070054899-A1 | Aromatase inhibitor compounds and uses thereof | PARALLEL WIRELESS, INC. | 2007-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070054899-A1 | Aromatase inhibitor compounds and uses thereof | CYP19A1, CYP17A1, HSD17B11 | OGT 2565/4885NOS1 418/4885GRIN2B 4032/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.