Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 9/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MLKL | Q8NB16 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8698994 | 0.87 | PSMB8 (0.64) | PSMB8KDM4EGAAALDH1A1KEAP1 | |
| SCHEMBL8701281 | 0.87 | PSMB8 (0.64) | PSMB8KDM4EGAAALDH1A1KEAP1 | |
| SCHEMBL8703017 | 0.83 | PSMB8 (0.46) | PSMB8KDM4EGAAALDH1A1KEAP1 | |
| SCHEMBL14565124 | 0.82 | OGT (0.50) | KDM4EALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL8701154 | 0.81 | PSMB8 (0.43) | PSMB8KDM4EGAAALDH1A1KEAP1 | |
| SCHEMBL8698930 | 0.78 | PSMB8 (0.43) | PSMB8KDM4EGAAALDH1A1KEAP1 | |
| SCHEMBL8702977 | 0.77 | GAA (0.44) | PSMB8KDM4EGAAALDH1A1KEAP1 | |
| SCHEMBL8697934 | 0.77 | KDM4E (0.44) | PSMB8KDM4EGAAALDH1A1KEAP1 | |
| SCHEMBL13508871 | 0.76 | PSMB8 (0.61) | PSMB8KDM4EGAAALDH1A1KEAP1 | |
| SCHEMBL14565145 | 0.70 | OGT (0.50) | EGFRPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025913-A1 | NOVEL SUBSTITUTED 3H -BENZOXAZOLE-2-THIONES AND 3H -BENZOTHIAZOLE-2 THIONES DERIVATIVES, METHOD FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1998-06-18 | — | — | WO | disclosed |