Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | BTK | Q06187 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10133315 | 1.00 | MAPT (0.59) | MAPTRAB9ALRRK2ALDH1A1BTK | |
| SCHEMBL14418345 | 1.00 | MAPT (0.59) | MAPTRAB9ALRRK2ALDH1A1BTK | |
| SCHEMBL21254717 | 0.84 | MAPT (0.53) | MAPTRAB9AALDH1A1 | |
| SCHEMBL14503960 | 0.80 | MAPT (0.58) | MAPTRAB9ALRRK2ALDH1A1BTK | |
| SCHEMBL13105197 | 0.80 | MAPT (0.66) | MAPTRAB9ALRRK2ALDH1A1 | |
| SCHEMBL13105222 | 0.80 | MAPT (0.66) | MAPTRAB9ALRRK2ALDH1A1 | |
| SCHEMBL20217488 | 0.79 | MAPT (0.44) | MAPTLRRK2ALDH1A1BTK | |
| SCHEMBL6224086 | 0.78 | TRIM24 (0.52) | MAPTRAB9AALDH1A1 | |
| SCHEMBL17360063 | 0.78 | TRIM24 (0.52) | MAPTRAB9AALDH1A1 | |
| SCHEMBL13222580 | 0.78 | ALDH1A1 (0.42) | MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1760073-A1 | SULFONAMIDE COMPOUND | SHIONOGI & CO., LTD. (JP) | 2007-03-07 | — | — | EP | disclosed |