Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.60 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.59 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.59 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.58 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.57 |
| ▸ | TYMS | P04818 | 1/20 | 0.57 |
| ▸ | TACR1 | P25103 | 4/20 | 0.57 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14565649 | 0.91 | KMT2A (0.55) | KMT2AMEN1HCRTR1NPBWR1MCHR1 | |
| SCHEMBL14565644 | 0.89 | ERAP2 (0.72) | LNPEPERAP2 | |
| SCHEMBL14565641 | 0.89 | MEN1 (0.52) | KMT2AMEN1HCRTR1NPBWR1MCHR1 | |
| SCHEMBL14565639 | 0.89 | NAMPT (0.66) | KMT2AMEN1HCRTR1NPBWR1MCHR1 | |
| SCHEMBL18620488 | 0.86 | KMT2A (0.64) | KMT2AMEN1HCRTR1NPBWR1MCHR1 | |
| SCHEMBL22292158 | 0.86 | KMT2A (0.64) | KMT2AMEN1HCRTR1NPBWR1MCHR1 | |
| SCHEMBL20356918 | 0.86 | KMT2A (0.64) | KMT2AMEN1HCRTR1NPBWR1MCHR1 | |
| SCHEMBL9088492 | 0.83 | TACR1 (0.64) | KMT2AMEN1HCRTR1NPBWR1MCHR1 | |
| SCHEMBL9088495 | 0.83 | TACR1 (0.64) | KMT2AMEN1HCRTR1NPBWR1MCHR1 | |
| SCHEMBL1921333 | 0.82 | NPC1 (0.62) | KMT2AMEN1HCRTR1NPBWR1MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189724-B2 | Quinoxaline derivatives having antiviral activity | VALEANT RESEARCH AND DEVELOPMENT (US) | 2007-03-13 | — | — | US | disclosed |
| US-7189724-B2 | Quinoxaline derivatives having antiviral activity | VALEANT RESEARCH AND DEVELOPMENT (US) | 2007-03-13 | — | — | US | disclosed |