Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.53 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.53 |
| ▸ | ITGAL | P20701 | 1/20 | 0.53 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.52 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.52 |
| ▸ | TYMS | P04818 | 1/20 | 0.51 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | TACR1 | P25103 | 3/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14565638 | 0.91 | NAMPT (0.69) | NAMPTITGB2ICAM1ITGALSCN9A | |
| SCHEMBL14565637 | 0.90 | NAMPT (0.53) | NAMPTMEN1KMT2AMAPTPOLB | |
| SCHEMBL14565640 | 0.90 | NAMPT (0.68) | NAMPTMEN1KMT2AITGB2ICAM1 | |
| SCHEMBL14565643 | 0.89 | KMT2A (0.60) | MEN1KMT2AHCRTR1NPBWR1MCHR1 | |
| SCHEMBL14565641 | 0.85 | MEN1 (0.52) | MEN1KMT2AHCRTR1NPBWR1MCHR1 | |
| SCHEMBL14565649 | 0.84 | KMT2A (0.55) | MEN1KMT2AHCRTR1NPBWR1MCHR1 | |
| SCHEMBL14565636 | 0.81 | NAMPT (0.56) | NAMPTKMT2AITGB2ICAM1ITGAL | |
| SCHEMBL14565635 | 0.80 | HPGDS (0.55) | NAMPTKMT2AITGB2ICAM1ITGAL | |
| SCHEMBL17195975 | 0.80 | NAMPT (1.00) | NAMPTMEN1KMT2A | |
| SCHEMBL22292158 | 0.79 | KMT2A (0.64) | MEN1KMT2AITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189724-B2 | Quinoxaline derivatives having antiviral activity | VALEANT RESEARCH AND DEVELOPMENT (US) | 2007-03-13 | — | — | US | disclosed |
| US-7189724-B2 | Quinoxaline derivatives having antiviral activity | VALEANT RESEARCH AND DEVELOPMENT (US) | 2007-03-13 | — | — | US | disclosed |