Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.72 |
| ▸ | ITGB2 | P05107 | 7/20 | 0.67 |
| ▸ | ICAM1 | P05362 | 7/20 | 0.67 |
| ▸ | ITGAL | P20701 | 7/20 | 0.67 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.59 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | ACE | P12821 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14565643 | 0.89 | KMT2A (0.60) | ERAP2LNPEP | |
| SCHEMBL14565642 | 0.88 | ERAP2 (0.62) | ERAP2ITGB2ICAM1ITGALBBOX1 | |
| SCHEMBL14565638 | 0.88 | NAMPT (0.69) | ERAP2ITGB2ICAM1ITGALBBOX1 | |
| SCHEMBL1232691 | 0.86 | ERAP2 (0.77) | ERAP2ITGB2ICAM1ITGALLNPEP | |
| SCHEMBL1232689 | 0.86 | ERAP2 (0.77) | ERAP2ITGB2ICAM1ITGALLNPEP | |
| SCHEMBL5259129 | 0.84 | ITGB2 (0.78) | ERAP2ITGB2ICAM1ITGALALOX15 | |
| SCHEMBL30616778 | 0.84 | ITGB2 (0.78) | ERAP2ITGB2ICAM1ITGALALOX15 | |
| SCHEMBL9466705 | 0.84 | ITGB2 (0.78) | ERAP2ITGB2ICAM1ITGALALOX15 | |
| SCHEMBL5191302 | 0.84 | ITGB2 (0.78) | ERAP2ITGB2ICAM1ITGALALOX15 | |
| SCHEMBL10518274 | 0.84 | CCKBR (0.75) | ERAP2ITGB2ICAM1ITGALBBOX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7189724-B2 | Quinoxaline derivatives having antiviral activity | VALEANT RESEARCH AND DEVELOPMENT (US) | 2007-03-13 | — | — | US | disclosed |
| US-7189724-B2 | Quinoxaline derivatives having antiviral activity | VALEANT RESEARCH AND DEVELOPMENT (US) | 2007-03-13 | — | — | US | disclosed |